Evidence mapPaperPMID 30513818Full record

Trial reportNutrients2018

Thromboxane-Dependent Platelet Activation in Obese Subjects with Prediabetes or Early Type 2 Diabetes: Effects of Liraglutide- or Lifestyle Changes-Induced Weight Loss.

Paola Simeone, Rossella Liani, Romina Tripaldi, Augusto Di Castelnuovo, Maria Teresa Guagnano, Armando Tartaro, Riccardo C Bonadonna, Virginia Federico, Francesco Cipollone, Agostino Consoli and 1 more

Open access · goldFull text readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Significance of 8-iso-PGFAmerican heart journal plus : cardiology research and practice · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Identification of novel FRedox biology · 2024
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Observational
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Paola SimeoneDepartment of Medicine and Aging and Center of Aging Science and Translational Medicine (CESI-Met), University of Chieti, 66100 Chieti, Italy. paolagsimeone@gmail.com.
Rossella LianiDepartment of Medicine and Aging and Center of Aging Science and Translational Medicine (CESI-Met), University of Chieti, 66100 Chieti, Italy. rossellaliani@yahoo.it.
Romina TripaldiDepartment of Medicine and Aging and Center of Aging Science and Translational Medicine (CESI-Met), University of Chieti, 66100 Chieti, Italy. romina.tripaldi@hotmail.it.
Augusto Di CastelnuovoDepartment of Epidemiology and Prevention, IRCCS NEUROMED, Via dell'Elettronica, 86077 Pozzilli, Italy. dicastel@ngi.it.
Maria Teresa GuagnanoDepartment of Medicine and Aging and Center of Aging Science and Translational Medicine (CESI-Met), University of Chieti, 66100 Chieti, Italy. guagnano@unich.it.
Armando TartaroDepartment of Neuroscience & Imaging, University of Chieti, 66100 Chieti, Italy. armando.tartaro@gmail.com.
Riccardo C BonadonnaDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy. bonadonna.riccardo@fastwebnet.it.
Virginia FedericoClinical Pathology, Chieti Hospital, 66100 Chieti, Italy. virgin83@virgilio.it.
Francesco CipolloneDepartment of Medicine and Aging and Center of Aging Science and Translational Medicine (CESI-Met), University of Chieti, 66100 Chieti, Italy. francesco.cipollone@unich.it.
Agostino ConsoliDepartment of Medicine and Aging and Center of Aging Science and Translational Medicine (CESI-Met), University of Chieti, 66100 Chieti, Italy. consoli@unich.it.
Francesca SantilliDepartment of Medicine and Aging and Center of Aging Science and Translational Medicine (CESI-Met), University of Chieti, 66100 Chieti, Italy. francesca.santilli@unich.it.
University of Chieti-Pescara · ITIstituto Neurologico Mediterraneo · ITOspedale di Parma · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca 2010JS3PMZ
6 · The paper itself

Abstract

Thromboxane (TX)-dependent platelet activation and lipid peroxidation, as reflected in vivo by the urinary excretion of 11-dehydro-TXB₂ and 8-iso-prostaglandin (PG)F

Indexed as

Life StyleBlood GlucoseDiabetes MellitusDiabetes Mellitus, Type 2DietDinoprostExerciseFemaleGlycated HemoglobinHumansLipid PeroxidationLiraglutideLongitudinal StudiesMaleMiddle AgedObesity11-dehydro-thromboxane B28-epi-prostaglandin F2alphaBlood GlucoseDinoprostGlycated HemoglobinLiraglutideThromboxane B2Thromboxanesadipose tissue distributiondiabetes mellitusliraglutideobesityoxidative stressplatelet activationweight loss

Identifiers

PMID30513818
PMCPMC6315606
OpenAlexW2903403054

What Socratic holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.