Evidence map›Paper›PMID 30519980›Full record

ReviewInternational urology and nephrology2019

The effect of chronic kidney disease on lipid metabolism.

Neris Dincer, Tuncay Dagel, Baris Afsar, Adrian Covic, Alberto Ortiz, Mehmet Kanbay

Abstract readReview
PubMed Publisher
In one paragraph

Review in International urology and nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. [Elevated advanced glycation endproducts is a risk factor for stenosis after primary arteriovenous fistula surgery].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
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  6. Review
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  13. Review
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  17. Article
  18. Progress of research on dyslipidemia accompanied by nephrotic syndrome.Chronic diseases and translational medicine · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Neris DincerDepartment of Medicine, Koc University School of Medicine, Istanbul, Turkey.
Tuncay DagelDivision of Nephrology, Department of Medicine, Koc University School of Medicine, 34010, Istanbul, Turkey.
Baris AfsarDivision of Nephrology, Department of Medicine, Suleyman Demirel University School of Medicine, Isparta, Turkey.
Adrian CovicNephrology Department, Dialysis and Renal Transplant Center, "Dr. C.I. Parhon" University Hospital, "Grigore T. Popa'' University of Medicine and Pharmacy, Iasi, Romania.
Alberto OrtizDialysis Unit, School of Medicine, IIS-Fundacion Jimenez Diaz, Universidad Autónoma de Madrid, Avd. Reyes Católicos 2, 28040, Madrid, Spain.
Mehmet KanbayDivision of Nephrology, Department of Medicine, Koc University School of Medicine, 34010, Istanbul, Turkey. drkanbay@yahoo.com.ORCID http://orcid.org/0000-0002-1297-0675
Koç University · TRGrigore T. Popa University of Medicine and Pharmacy · ROSüleyman Demirel University · TRUniversidad Autónoma de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The major cause of death among chronic kidney disease patients is cardiovascular diseases. Cardiovascular and kidney disease are interrelated and increase the severity of each other. Dyslipidemia is one the major causes of cardiovascular disease among chronic kidney disease patients along with diabetes and hypertension. The relationship between dyslipidemia and chronic kidney disease is reciprocal. Dyslipidemia is known to be a risk factor for chronic kidney disease and chronic kidney disease causes major alterations on lipoprotein profile, defined as the "dyslipidemic profile" of chronic kidney disease patients. Increased triglyceride, very low density lipoprotein and oxidized low density lipoprotein as well as decreased high density lipoprotein and changes in the composition of lipoproteins contribute to the "dyslipidemic profile." Treatment strategies targeting the "dyslipidemic profile" of chronic kidney disease could contribute to prevent cardiovascular diseases. Current therapy is based on the patient kidney function and consist mainly of statins. This review focuses on the effects of chronic kidney disease on the lipoprotein profile and how this may impact novel therapeutic approaches to cardiovascular risk.

Indexed as

DyslipidemiasRenal Insufficiency, ChronicCardiovascular DiseasesHumansLipid MetabolismRisk FactorsCholesterolChronic kidney diseaseHDLLDLPCSK9Triglycerides

Identifiers

PMID30519980
OpenAlexW2902868978

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.