Evidence map›Paper›PMID 30526863›Full record

ArticleAmerican journal of human genetics2018

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Despoina Manousaki, Tom Dudding, Simon Haworth, Yi-Hsiang Hsu, Ching-Ti Liu, Carolina Medina-Gómez, Trudy Voortman, Nathalie van der Velde, Håkan Melhus, Cassianne Robinson-Cohen and 43 more

Abstract readPublished Erratum
In one paragraph

Article in American journal of human genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

53 authors.

Despoina Manousaki
Tom Dudding
Simon Haworth
Yi-Hsiang Hsu
Ching-Ti Liu
Carolina Medina-Gómez
Trudy Voortman
Nathalie van der Velde
Håkan Melhus
Cassianne Robinson-Cohen
Diana L Cousminer
Maria Nethander
Liesbeth Vandenput
Raymond Noordam
Vincenzo Forgetta
Celia M T Greenwood
Mary L Biggs
Bruce M Psaty
Jerome I Rotter
Babette S Zemel
Jonathan A Mitchell
Bruce Taylor
Mattias Lorentzon
Magnus Karlsson
Vincent V W Jaddoe
Henning Tiemeier
Natalia Campos-Obando
Oscar H Franco
Andre G Utterlinden
Linda Broer
Natasja M van Schoor
Annelies C Ham
M Arfan Ikram
David Karasik
Renée de Mutsert
Frits R Rosendaal
Martin den Heijer
Thomas J Wang
Lars Lind
Eric S Orwoll
Dennis O Mook-Kanamori
Karl Michaëlsson
Bryan Kestenbaum
Claes Ohlsson
Dan Mellström
Lisette C P G M de Groot
Struan F A Grant
Douglas P Kiel
M Carola Zillikens
Fernando Rivadeneira
Stephen Sawcer
Nicholas J Timpson
J Brent Richards

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID30526863
PMCPMC6288274

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.