Evidence map›Paper›PMID 30541452›Full record

ArticleBMC genomics2018

Screening of Streptococcus Suis serotype 2 resistance genes with GWAS and transcriptomic microarray analysis.

Zhe Ma, Haodan Zhu, Yiqi Su, Yu Meng, Huixing Lin, Kongwang He, Hongjie Fan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Inhibitory Effect of Piceatannol onFrontiers in microbiology · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhe MaMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Haodan ZhuJiangsu Academy Agricultural Sciences, Nanjing, 210095, China.
Yiqi SuMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Yu MengMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Huixing LinMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Kongwang HeJiangsu Academy Agricultural Sciences, Nanjing, 210095, China.
Hongjie FanMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China. fhj@njau.edu.cn.
Nanjing Agricultural University · CNJiangsu Academy of Agricultural Sciences · CN

Funding

China Scholarship Council 201706855039Special Fund for Agro-scientific Research in the Public Interest 201403054the Jiangsu Province Science and Technology Support Program BE2013433the Key Project of Independent Innovation of the Fundamental Research Fund for the Central Universities of Nanjing Agricultural University KYZ201630the National Key Research and Development Program 2016YFD0501607the National Natural Science Foundation of China 31772746, 31302093, 31272581the National Transgenic Major Program 2014ZX0800946Bthe Natural Science Foundation of Jiangsu Province BK20130676the Priority Academic Program Development of Jiangsu Higher Education Institutions PAPD
6 · The paper itself

Abstract

backgroundSwine streptococcosis has caused great economic loss in the swine industry, and the major pathogen responsible for this disease is Streptococcus Suis serotype 2 (SS2). Disease resistance breeding is a fundamental way of resolving this problem. With the development of GWAS and transcriptomic microarray technology, we now have powerful research tools to identify SS2 resistance genes.

resultsIn this research, we generated an F

conclusionThis is the first study to use both SNP chip and gene express profile chip for SS2 resistance gene identification in mouse, and these results will contribute to swine SS2 resistance breeding.

Indexed as

Genome-Wide Association StudyTranscriptomeAdaptor Proteins, Vesicular TransportAnimalsDisease ResistanceFemaleGene Expression ProfilingGenomeMaleMiceMice, Inbred C57BLOligonucleotide Array Sequence AnalysisPolymorphism, Single NucleotideSerogroupStreptococcal InfectionsStreptococcus suisAdaptor Proteins, Vesicular TransportepsinUbiquitin-Protein Ligase ComplexesGenome-wide association studyResistance genesStreptococcus suis serotype 2Transcriptome analysis

Identifiers

PMID30541452
PMCPMC6292034
OpenAlexW2904074423

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.