Evidence map›Paper›PMID 30545748›Full record

Trial reportSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2019

Effect of alcohol ingestion on plasma glucose kinetics after Roux-en-Y gastric bypass surgery.

María Belén Acevedo, Ramiro Ferrando, Bruce W Patterson, J Christopher Eagon, Samuel Klein, Marta Yanina Pepino

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

María Belén AcevedoDepartment of Food Science and Human Nutrition, College of Agricultural, Consumer and Environmental Sciences, University of Illinois, Urbana-Champaign, Illinois.
Ramiro FerrandoDepartment of Food Science and Human Nutrition, College of Agricultural, Consumer and Environmental Sciences, University of Illinois, Urbana-Champaign, Illinois.
Bruce W PattersonCenter for Human Nutrition and Atkins Center of Excellence in Obesity Medicine, Washington University School of Medicine, St. Louis, Missouri.
J Christopher EagonCenter for Human Nutrition and Atkins Center of Excellence in Obesity Medicine, Washington University School of Medicine, St. Louis, Missouri; Department of Surgery, Washington University School of Medicine, St. Louis, Missouri.
Samuel KleinCenter for Human Nutrition and Atkins Center of Excellence in Obesity Medicine, Washington University School of Medicine, St. Louis, Missouri.
Marta Yanina PepinoDepartment of Food Science and Human Nutrition, College of Agricultural, Consumer and Environmental Sciences, University of Illinois, Urbana-Champaign, Illinois; Division of Nutritional Sciences, College of Agricultural, Consumer and Environmental Sciences, University of Illinois, Urbana-Champaign, Illinois. Electronic address: ypepino@illinois.edu.
Atkins (United States) · USUniversity of Illinois Urbana-Champaign · US

Funding

Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Nada A. Abumrad · 1999 to 2026
$30.2M
PHARMACOKINETICS AND SUBJECTIVE RESPONSES TO ALCOHOL AFTER BARIATRIC SURGERYR01AA024103 · NIAAA · WASHINGTON UNIVERSITY · PI MARTA YANINA PEPINO DE GRUEV · 2016 to 2026
$3.0M
WEIGHT LOSS-INDEPENDENT METABOLIC EFFECTS OF ROUX-EN-Y GASTRIC BYPASS IN DIABETESR01DK101578 · NIDDK · WASHINGTON UNIVERSITY · PI KLEIN, SAMUEL · 2014 to 2018
$2.5M
PHARMACOKINETICS AND PHARMACOLOGICAL EFFECTS OF ALCOHOL AFTER BARIATRIC SURGERYR21AA020018 · NIAAA · WASHINGTON UNIVERSITY · PI PEPINO DE GRUEV, MARTA YANINA · 2012 to 2013
$404k
NIAAA NIH HHS R01 AA024103NIAAA NIH HHS R21 AA020018NIDDK NIH HHS P30 DK056341NIDDK NIH HHS R01 DK101578
6 · The paper itself

Abstract

backgroundRoux-en-Y gastric bypass surgery (RYGB) increases the rate of alcohol absorption so that peak blood alcohol concentration is 2-fold higher after surgery compared with concentrations reached after consuming the same amount presurgery. Because high doses of alcohol can lead to hypoglycemia, patients may be at increased risk of developing hypoglycemia after alcohol ingestion.

objectivesWe conducted 2 studies to test the hypothesis that the consumption of approximately 2 standard drinks of alcohol would decrease glycemia more after RYGB than before surgery.

settingSingle-center prospective randomized trial.

methodsWe evaluated plasma glucose concentrations and glucose kinetics (assessed by infusing a stable isotopically labelled glucose tracer) after ingestion of a nonalcoholic drink (placebo) or an alcoholic drink in the following groups: (1) 5 women before RYGB (body mass index = 43 ± 5 kg/m

conclusionRYGB does not increase the risk of hypoglycemia after consumption of a moderate dose of alcohol.

Indexed as

Gastric BypassAlcohol DrinkingBlood GlucoseBody Mass IndexFemaleHumansHypoglycemiaObesity, MorbidBlood GlucoseAlcoholBariatric surgeryEthanolGlucoseGlucose kineticsGlycemiaHypoglycemiaMetabolic surgery

Identifiers

PMID30545748
PMCPMC6441624
OpenAlexW2898938879

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.