Evidence map›Paper›PMID 30545930›Full record

ArticleHaematologica2019

Downregulation of TREM-like transcript-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia.

Ana C Glembotsky, Dominika Sliwa, Dominique Bluteau, Nathalie Balayn, Cecilia P Marin Oyarzún, Anna Raimbault, Marie Bordas, Nathalie Droin, Iryna Pirozhkova, Valance Washington and 5 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. T-TASBlood transfusion = Trasfusione del sangue · 2024
    Article
  6. Article
  7. The biology of TREM receptors.Nature reviews. Immunology · 2023
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Ana C GlembotskyInstituto de Investigaciones Médicas Alfredo Lanari, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
Dominika SliwaINSERM UMR 1170, Gustave Roussy, Université Paris-Saclay, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villejuif, Franc
Dominique BluteauINSERM UMR 1170, Gustave Roussy, Université Paris-Saclay, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villejuif, Franc
Nathalie BalaynINSERM UMR 1170, Gustave Roussy, Université Paris-Saclay, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villejuif, Franc
Cecilia P Marin OyarzúnInstituto de Investigaciones Médicas Alfredo Lanari, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
Anna RaimbaultINSERM UMR 1170, Gustave Roussy, Université Paris-Saclay, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villejuif, Franc
Marie BordasINSERM UMR 1170, Gustave Roussy, Université Paris-Saclay, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villejuif, Franc
Nathalie DroinINSERM UMR 1170, Gustave Roussy, Université Paris-Saclay, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villejuif, Franc
Iryna PirozhkovaCNRS UMR 8126, Gustave Roussy, Université Paris-Saclay, Villejuif, France
Valance WashingtonDepartment of Biology, University of Puerto Rico-Rio Piedras, San Juan, Puerto Rico and
Nora P GoetteInstituto de Investigaciones Médicas Alfredo Lanari, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
Rosana F MartaInstituto de Investigaciones Médicas Alfredo Lanari, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
Rémi FavierINSERM UMR 1170, Gustave Roussy, Université Paris-Saclay, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villejuif, Franc
Hana RaslovaINSERM UMR 1170, Gustave Roussy, Université Paris-Saclay, Equipe Labellisée par la Ligue Nationale Contre le Cancer, Villejuif, Franc
Paula G HellerInstituto de Investigaciones Médicas Alfredo Lanari, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
La Ligue Contre le Cancer · FRUniversity of Buenos Aires · ARInstitute for Medical Research · ARInstitut Gustave Roussy · FRUniversité Paris-Saclay · FRInserm · FRSorbonne Université · FRUniversity of Puerto Rico at Río Piedras · PR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Germline

Indexed as

Gene Expression RegulationBlood Platelet DisordersBlood PlateletsCore Binding Factor Alpha 2 SubunitDisease SusceptibilityGene Expression ProfilingHumansIntegrin alpha2Leukemia, Myeloid, AcuteMegakaryocytesMutationPlatelet AggregationPlatelet Function TestsProtein BindingReceptors, ImmunologicCore Binding Factor Alpha 2 SubunitIntegrin alpha2ITGA2B protein, humanReceptors, ImmunologicRUNX1 protein, humanTREML1 protein, human

Identifiers

PMID30545930
PMCPMC6545826
OpenAlexW2904471261

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.