Evidence map›Paper›PMID 30546002›Full record

ArticleGenetics2019

Glucose Signaling Is Connected to Chromosome Segregation Through Protein Kinase A Phosphorylation of the Dam1 Kinetochore Subunit in

Sameer B Shah, David Parmiter, Christian Constantine, Paul Elizalde, Michael Naldrett, Tatiana S Karpova, John S Choy

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A yeast-based system to study SARS-CoV-2 MbioRxiv : the preprint server for biology · 2022
    Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Sameer B ShahDepartment of Biology, The Catholic University of America, Washington, DC 20064.
David ParmiterDepartment of Biology, The Catholic University of America, Washington, DC 20064.
Christian ConstantineDepartment of Biology, The Catholic University of America, Washington, DC 20064.
Paul ElizaldeDepartment of Biology, The Catholic University of America, Washington, DC 20064.
Michael NaldrettProteomics and Metabolomics Facility Center for Biotechnology, Beadle Center, University of Nebraska-Lincoln, Nebraska 68588.
Tatiana S KarpovaLaboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
John S ChoyDepartment of Biology, The Catholic University of America, Washington, DC 20064 choy@cua.edu.
University of America · USCatholic University of America · USNational Institutes of Health · USUniversity of Nebraska–Lincoln · US

Funding

LRBGE Optical Microscopy CoreZICBC011574 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KARPOVA, TATIANA · 2014 to 2025
$7.4M
6 · The paper itself

Abstract

The Dam1 complex is an essential component of the outer kinetochore that mediates attachments between spindle microtubules and chromosomes. Dam1p, a subunit of the Dam1 complex, binds to microtubules and is regulated by Aurora B/Ipl1p phosphorylation. We find that overexpression of cAMP-dependent protein kinase (PKA) catalytic subunits (

Indexed as

Chromosome SegregationCell Cycle ProteinsCyclic AMP-Dependent Protein KinasesGlucoseKinetochoresMicrotubule-Associated ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionCell Cycle ProteinsCyclic AMP-Dependent Protein KinasesDAM1 protein, S cerevisiaeGlucoseMicrotubule-Associated ProteinsSaccharomyces cerevisiae Proteinschromosome segregationDam1 complexDam1p subunitglucose signalingkinetochoreRas/PKA

Identifiers

PMID30546002
PMCPMC6366914
OpenAlexW2904927731

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.