Evidence map›Paper›PMID 30552148›Full record

ArticleEMBO reports2019

The key protein of endosomal mRNP transport Rrm4 binds translational landmark sites of cargo mRNAs.

Lilli Olgeiser, Carl Haag, Susan Boerner, Jernej Ule, Anke Busch, Janine Koepke, Julian König, Michael Feldbrügge, Kathi Zarnack

Open access · bronzeAbstract read
In one paragraph

Article in EMBO reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
  3. The RRM domain-containing protein Rbp3 interacts with ribosomes and the 3' ends of mRNAs encoding photosynthesis proteins.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Deciphering the RNA-binding protein network during endosomal mRNA transport.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  6. Review
  7. Article
  8. The mRNA stability factor Khd4 defines a specific mRNA regulon for membrane trafficking in the pathogenProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Sodium butyrate induces ferroptosis in endometrial cancer cells via the RBM3/SLC7A11 axis.Apoptosis : an international journal on programmed cell death · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. mRNA Inventory of Extracellular Vesicles fromJournal of fungi (Basel, Switzerland) · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Lilli OlgeiserInstitute for Microbiology, Cluster of Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Carl HaagInstitute for Microbiology, Cluster of Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Susan BoernerBuchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt, Frankfurt am Main, Germany.
Jernej UleThe Francis Crick Institute, London, UK.ORCID 0000-0002-2452-4277
Anke BuschInstitute of Molecular Biology gGmbH, Mainz, Germany.
Janine KoepkeMedical Clinic II (Molecular Pneumology), Excellence Cluster Cardio-Pulmonary System, Justus Liebig University of Gießen, Gießen, Germany.
Julian KönigInstitute of Molecular Biology gGmbH, Mainz, Germany.
Michael FeldbrüggeInstitute for Microbiology, Cluster of Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, Düsseldorf, Germany feldbrue@hhu.de kathi.zarnack@bmls.de.ORCID 0000-0003-0046-983X
Kathi ZarnackBuchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt, Frankfurt am Main, Germany feldbrue@hhu.de kathi.zarnack@bmls.de.ORCID 0000-0003-3527-3378
Cluster of Excellence on Plant Sciences · DEGoethe University Frankfurt · DEInstitute of Molecular Biology · DEJustus-Liebig-Universität Gießen · DEThe Francis Crick Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA-binding proteins (RBPs) determine spatiotemporal gene expression by mediating active transport and local translation of cargo mRNAs. Here, we cast a transcriptome-wide view on the transported mRNAs and cognate RBP binding sites during endosomal messenger ribonucleoprotein (mRNP) transport in

Indexed as

Binding SitesBiological TransportEndosomesFungal ProteinsGene Expression RegulationMicrotubulesRibonucleoproteinsRNA-Binding ProteinsRNA, MessengerRNA TransportTranscriptomeUstilagoFungal Proteinsmessenger ribonucleoproteinRibonucleoproteinsRNA-Binding ProteinsRNA, MessengerendosomefungusiCLIPRNA transport

Identifiers

PMID30552148
PMCPMC6322384
OpenAlexW2949263620

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.