Evidence map›Paper›PMID 30559742›Full record

ArticleFrontiers in immunology2018

Disease Tolerance and Pathogen Resistance Genes May Underlie

Christophe Chevillard, João Paulo Silva Nunes, Amanda Farage Frade, Rafael Ribeiro Almeida, Ramendra Pati Pandey, Marilda Savóia Nascimento, Jorge Kalil, Edecio Cunha-Neto

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 4 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 4 syntheses or guidelines pooled it, 69 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Observational
  8. Review
  9. Review
  10. Review
  11. Review
  12. Chagas disease in immunocompromised patients.Clinical microbiology reviews · 2024
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Exhausted PD-1Frontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Christophe ChevillardINSERM UMR 1090, TAGC, Aix-Marseille Université, Marseille, France.
João Paulo Silva NunesLaboratorio de Imunologia, Instituto do Coracao, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.
Amanda Farage FradeLaboratorio de Imunologia, Instituto do Coracao, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.
Rafael Ribeiro AlmeidaLaboratorio de Imunologia, Instituto do Coracao, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.
Ramendra Pati PandeyLaboratorio de Imunologia, Instituto do Coracao, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.
Marilda Savóia NascimentoLaboratorio de Imunologia, Instituto do Coracao, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.
Jorge KalilLaboratorio de Imunologia, Instituto do Coracao, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.
Edecio Cunha-NetoLaboratorio de Imunologia, Instituto do Coracao, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRAix-Marseille Université · FRUniversidade Brasil · BR

Funding

Sao Paulo-Minas Gerais Tropical Medicine Research Center for Chagas Disease Biomarker DiscoveryU19AI098461 · NIAID · FUNDACAO FACULDADE DE MEDICINA · PI PEREIRA, ALEXANDRE DA COSTA · 2017 to 2021
$2.1M
NIAID NIH HHS U19 AI098461
6 · The paper itself

Abstract

Chagas disease is caused by infection with the protozoan

Indexed as

Chagas CardiomyopathyChagas DiseaseDisease ProgressionHeartHumansImmune ToleranceInterferon-gammaInterleukin-10Th1 CellsTrypanosoma cruziInterferon-gammaInterleukin-10chagas cardiomyopathydisease tolerance geneinterferon gammapathogen resistance genesTripanosoma cruzi

Identifiers

PMID30559742
PMCPMC6286977
OpenAlexW2902847939

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.