Evidence map›Paper›PMID 30560870›Full record

ArticleNature communications2018

Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks.

Ang Li, Jung-Hwa Cho, Brian Reid, Chun-Chih Tseng, Lian He, Peng Tan, Chao-Yuan Yeh, Ping Wu, Yuwei Li, Randall B Widelitz and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Developing Optogenetic Approaches to Study CaCold Spring Harbor perspectives in biology · 2026
    Review
  3. Article
  4. Bioelectric state transitions enablebioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Intracellular CaBMC molecular and cell biology · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Autophagy-Mediated Suppression of Tumor Growth by Food-Grade Lipid Nanoparticles in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Ang LiDept. of Pathology, USC Keck School of Medicine, Los Angeles, CA, 90033, USA.
Jung-Hwa ChoDept. of Physiology & Biophysics, USC Keck School of Medicine, Los Angeles, CA, 90033, USA.
Brian ReidDept. of Dermatology, UC Davis School of Medicine, Sacramento, CA, 95817, USA.
Chun-Chih TsengDept. of Pathology, USC Keck School of Medicine, Los Angeles, CA, 90033, USA.
Lian HeInstitute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX, 77030, USA.
Peng TanInstitute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX, 77030, USA.
Chao-Yuan YehDept. of Pathology, USC Keck School of Medicine, Los Angeles, CA, 90033, USA.
Ping WuDept. of Pathology, USC Keck School of Medicine, Los Angeles, CA, 90033, USA.
Yuwei LiDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
Randall B WidelitzDept. of Pathology, USC Keck School of Medicine, Los Angeles, CA, 90033, USA.
Yubin ZhouInstitute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX, 77030, USA.ORCID http://orcid.org/0000-0001-7962-0517
Min ZhaoDept. of Dermatology, UC Davis School of Medicine, Sacramento, CA, 95817, USA.ORCID http://orcid.org/0000-0002-2500-3035
Robert H ChowDept. of Physiology & Biophysics, USC Keck School of Medicine, Los Angeles, CA, 90033, USA. rchow@med.usc.edu.
Cheng-Ming ChuongDept. of Pathology, USC Keck School of Medicine, Los Angeles, CA, 90033, USA. cmchuong@med.usc.edu.
Keck Hospital of USC · USTexas A&M University · USChina Medical University · TWUniversity of California, Davis · USCalifornia Institute of Technology · USThe University of Texas at Arlington · US

Funding

USC RESEARCH CENTER FOR LIVER DISEASES: PILOT PROGRAMSP30DK048522 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAPLOWITZ, NEIL · 1995 to 2020
$21.8M
VISION RESEARCH CORE GRANTP30EY012576 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI W MARTIN USREY · 1999 to 2026
$18.9M
Size regulation of skin appendagesR01AR047364 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Cheng-Ming Chuong · 2002 to 2026
$10.1M
Molecular Generators at Corneal Wounds Produce and regulate the Wound Electrical SignalsR01EY019101 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ZHAO, MIN · 2010 to 2023
$5.2M
Tissue Engineering of New Hair FormationR01AR060306 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHUONG, CHENG-MING · 2010 to 2019
$4.6M
Experimental and Clinical Investigations of Retinal StimulationR01EY022931 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI WEILAND, JAMES D. · 2013 to 2017
$4.5M
Tissue Patterning in living skin and organ explantsR37AR060306 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Cheng-Ming Chuong · 2020 to 2026
$3.6M
MOLECULAR CONTROL OF CALCIUM INFLUX AT THE ER-PLASMA MEMBRANE JUNCTIONSR01GM112003 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ZHOU, YUBIN · 2014 to 2022
$2.7M
Tissue mechanics in regenerative wound healing of the skinR01GM125322 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHUONG, CHENG-MING · 2018 to 2021
$1.3M
Optogenetic toolkit for remote control of voltage-gated calcium channelsR21GM126532 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HAN, GANG, ZHOU, YUBIN · 2018 to 2019
$443k
NEI NIH HHS P30 EY012576NEI NIH HHS R01 EY019101NEI NIH HHS R01 EY022931NIAMS NIH HHS R01 AR047364NIAMS NIH HHS R01 AR060306NIAMS NIH HHS R37 AR060306NIDDK NIH HHS P30 DK048522NIGMS NIH HHS R01 GM112003NIGMS NIH HHS R01 GM125322NIGMS NIH HHS R21 GM126532NIH HHS AR60306NIH HHS GM125322NIH HHS R01-AR47364
6 · The paper itself

Abstract

Collective cell migration mediates multiple tissue morphogenesis processes. Yet how multi-dimensional mesenchymal cell movements are coordinated remains mostly unknown. Here we report that coordinated mesenchymal cell migration during chicken feather elongation is accompanied by dynamic changes of bioelectric currents. Transcriptome profiling and functional assays implicate contributions from functional voltage-gated Ca

Indexed as

AnimalsCalcium SignalingCell MovementCells, CulturedChickensConnexin 43Embryo, NonmammalianFeathersGap JunctionsHedgehog ProteinsMesodermMorphogenesisPromoter Regions, GeneticSkinWnt Signaling PathwayConnexin 43Hedgehog Proteins

Identifiers

PMID30560870
PMCPMC6299091
OpenAlexW2905478280

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.