ArticleJournal of bone metabolism2018
Age-related Reference Intervals for Total Collagen-I-N-terminal Propeptide in Healthy Korean Population.
Article in Journal of bone metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Update on the role of bone turnover markers in the diagnosis and management of osteoporosis: a consensus paper from The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), International Osteoporosis Foundation (IOF), and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Review
- Long-term second-generation antipsychotics decreases bone formation and resorption in male patients with schizophrenia.Psychopharmacology · 2024Article
- The Use of Bone-Turnover Markers in Asia-Pacific Populations.Annals of laboratory medicine · 2024Review
- Serum levels of bone turnover markers including calculation ofBone reports · 2023Article
- Effectiveness and Usefulness of Bone Turnover Marker in Osteoporosis Patients: A Multicenter Study in Korea.Journal of bone metabolism · 2023Article
- Number of contiguous vertebral cross-links in the spine indicates bone formation: a cross-sectional study.BMC musculoskeletal disorders · 2023Article
- Intra-Individual Changes in Total Procollagen-Type 1 N-terminal Propeptide in a Korean Adult Population.Diagnostics (Basel, Switzerland) · 2022Article
- Potential Biomarkers to Improve the Prediction of Osteoporotic Fractures.Endocrinology and metabolism (Seoul, Korea) · 2020Review
- Reference Intervals for Bone Turnover Markers in Korean Healthy Women.Journal of bone metabolism · 2020Article
- Serum Procollagen Type I N-Terminal Propeptide and Osteocalcin Levels in Korean Children and Adolescents.Yonsei medical journal · 2019Article
- Clinical Application of Bone Turnover Markers in Osteoporosis in Korea.Journal of bone metabolism · 2019Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProcollagen type I N-terminal propeptide (PINP) is one of the most clinically useful bone formation biomarkers. Therefore, the purpose of this study was to independently evaluate the performance of automated total PINP assay and established age- and gender-specific reference intervals for PINP in healthy Korean population.
methodsThe imprecision, linearity, and detection capability of Elecsys total PINP assay was determined and reference interval was established using 599 serums from Korean population with normal bone mineral densities based on bone densitometry. Age groups were divided into 20s, 30s, 40s, 50s, 60s and over.
resultsElecsys total PINP had excellent performance in imprecision, linearity, and detection capability. When partitioning age groups in Korean male and female populations, there was significant difference in total PINP between different age groups. In male populations, PINP level was decreased with increasing age, then it remained steady after middle-age. In female populations, there was a decreasing tendency similar to that in the male population with a sharp increase in the 50 to 59 age group.
conclusionsElecsys total PINP assay showed precise and reliable performance in our study. We established age-related PINP reference intervals for Korean male and female population with normal bone mineral densities.
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