Evidence map›Paper›PMID 30576716›Full record

Trial reportExperimental gerontology2019

Effect of all-extremity high-intensity interval training vs. moderate-intensity continuous training on aerobic fitness in middle-aged and older adults with type 2 diabetes: A randomized controlled trial.

Chueh-Lung Hwang, Jisok Lim, Jeung-Ki Yoo, Han-Kyul Kim, Moon-Hyon Hwang, Eileen M Handberg, John W Petersen, Brady J Holmer, Julio A Leey Casella, Kenneth Cusi and 1 more

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Experimental gerontology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 11 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 11 syntheses or guidelines pooled it, 102 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Chueh-Lung HwangDepartment of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL, United States of America.
Jisok LimDepartment of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL, United States of America.
Jeung-Ki YooDepartment of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL, United States of America.
Han-Kyul KimDepartment of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL, United States of America.
Moon-Hyon HwangDepartment of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL, United States of America; Division of Health and Exercise Science, Incheon National University, Incheon, Republic of Korea.
Eileen M HandbergDivision of Cardiovascular Medicine, University of Florida, Gainesville, FL, United States of America.
John W PetersenDivision of Cardiovascular Medicine, University of Florida, Gainesville, FL, United States of America.
Brady J HolmerDepartment of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL, United States of America.
Julio A Leey CasellaDivision of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL, United States of America.
Kenneth CusiDivision of Endocrinology, Diabetes and Metabolism, University of Florida, Gainesville, FL, United States of America.
Demetra D ChristouDepartment of Applied Physiology & Kinesiology, University of Florida, Gainesville, FL, United States of America. Electronic address: ddchristou@ufl.edu.
University of Florida · USIncheon National University · KR

Funding

Endothelial Dysfunction in Older Adults with Type 2 Diabetes: Effect of ExerciseR21AG050203 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTOU, DEMETRA · 2015 to 2015
$225k
NIA NIH HHS R21 AG050203
6 · The paper itself

Abstract

Aging and diabetes are associated with decreased aerobic fitness, an independent predictor of mortality. Aerobic exercise is prescribed to improve aerobic fitness; however, middle-aged/older diabetic patients often suffer from mobility limitations which restrict walking. Non-weight-bearing/low-impact exercise is recommended but the optimal exercise prescription is uncertain. The goal of this randomized controlled trial was twofold: 1) to test if high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT), implemented on a non-weight-bearing all-extremity ergometer, are feasible, well-tolerated and safe in middle-aged/older adults with type 2 diabetes; and 2) to test whether all-extremity HIIT is more effective in improving aerobic fitness than MICT. A total of 58 sedentary individuals with type 2 diabetes (46 to 78 years; 63 ± 1) were randomized to all-extremity HIIT (n = 23), MICT (n = 19) or non-exercise control (CONT; n = 16). All-extremity HIIT and MICT, performed 4×/week for 8 weeks under supervision, resulted in no adverse events requiring hospitalization or medical treatment. Aerobic fitness (VO

Indexed as

Physical FitnessDiabetes Mellitus, Type 2Feasibility StudiesFemaleHigh-Intensity Interval TrainingHumansMaleMiddle AgedSedentary BehaviorAerobic fitnessAgingAll-extremity aerobic exerciseCardiovascular disease riskDiabetesVO(2peak)

Identifiers

PMID30576716
PMCPMC6404965
OpenAlexW2904544646

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.