Evidence map›Paper›PMID 30583549›Full record

ReviewCancers2018

Non-Coding RNAs in Glioma.

Ryte Rynkeviciene, Julija Simiene, Egle Strainiene, Vaidotas Stankevicius, Jurgita Usinskiene, Edita Miseikyte Kaubriene, Ingrida Meskinyte, Jonas Cicenas, Kestutis Suziedelis

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Targeting BRD4-A Promising Therapeutic Option for Glioblastoma?International journal of molecular sciences · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. LncRNA LINC00466 Promotes the Progression of Breast CancerCurrent pharmaceutical biotechnology · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ryte RynkevicieneNacional Cancer Institute, Santariskiu str. 1, LT-08660 Vilnius, Lithuania. ryte.rynkeviciene@nvi.lt.
Julija SimieneNacional Cancer Institute, Santariskiu str. 1, LT-08660 Vilnius, Lithuania. julija.fadejeva@nvi.lt.
Egle StrainieneNacional Cancer Institute, Santariskiu str. 1, LT-08660 Vilnius, Lithuania. egle.strainiene@nvi.lt.
Vaidotas StankeviciusNacional Cancer Institute, Santariskiu str. 1, LT-08660 Vilnius, Lithuania. vaidotas.stankevicius@nvi.lt.
Jurgita UsinskieneNacional Cancer Institute, Santariskiu str. 1, LT-08660 Vilnius, Lithuania. jurgita.usinskiene@nvi.lt.
Edita Miseikyte KaubrieneNacional Cancer Institute, Santariskiu str. 1, LT-08660 Vilnius, Lithuania. edita.kaubriene@nvi.lt.
Ingrida MeskinyteProteomics Center, Institute of Biochemistry, Vilnius University Life Sciences Center, Sauletekio al. 7, LT-10257 Vilnius, Lithuania. ingrida.meskinyte@gmail.com.
Jonas CicenasProteomics Center, Institute of Biochemistry, Vilnius University Life Sciences Center, Sauletekio al. 7, LT-10257 Vilnius, Lithuania. j.cicenas@mapkinases.eu.ORCID 0000-0002-9365-1843
Kestutis SuziedelisNacional Cancer Institute, Santariskiu str. 1, LT-08660 Vilnius, Lithuania. kestutis.suziedelis@gf.vu.lt.ORCID 0000-0002-9485-3674
Vilnius University · LTNational Cancer Institute · LTVilnius Gediminas Technical University · LT

Funding

Research Council of Lithuania MIP-015/2014
6 · The paper itself

Abstract

Glioma is the most aggressive brain tumor of the central nervous system. The ability of glioma cells to migrate, rapidly diffuse and invade normal adjacent tissue, their sustained proliferation, and heterogeneity contribute to an overall survival of approximately 15 months for most patients with high grade glioma. Numerous studies indicate that non-coding RNA species have critical functions across biological processes that regulate glioma initiation and progression. Recently, new data emerged, which shows that the cross-regulation between long non-coding RNAs and small non-coding RNAs contribute to phenotypic diversity of glioblastoma subclasses. In this paper, we review data of long non-coding RNA expression, which was evaluated in human glioma tissue samples during a five-year period. Thus, this review summarizes the following: (I) the role of non-coding RNAs in glioblastoma pathogenesis, (II) the potential application of non-coding RNA species in glioma-grading, (III) crosstalk between lncRNAs and miRNAs (IV) future perspectives of non-coding RNAs as biomarkers for glioma.

Indexed as

gliomalncRNAmiRNAnon-coding RNA

Identifiers

PMID30583549
PMCPMC6356972
OpenAlexW2906376872

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.