Evidence map›Paper›PMID 30586923›Full record

ReviewJournal of functional biomaterials2018

A Critical Review on Selected External Physical Cues and Modulation of Cell Behavior: Magnetic Nanoparticles, Non-thermal Plasma and Lasers.

Barbora Smolková, Mariia Uzhytchak, Anna Lynnyk, Šárka Kubinová, Alexandr Dejneka, Oleg Lunov

Abstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Systemic Effect of Thermo-Photobiomodulation on Mesenchymal Stem Cells.Bulletin of experimental biology and medicine · 2025
    Article
  2. Review
  3. Article
  4. Review
  5. On the Evaluation of the Hyperthermic Efficiency of Magnetic Scaffolds.IEEE open journal of engineering in medicine and biology · 2024
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Barbora SmolkováInstitute of Physics of the Czech Academy of Sciences, 18221 Prague, Czech Republic. smolkova@fzu.cz.
Mariia UzhytchakInstitute of Physics of the Czech Academy of Sciences, 18221 Prague, Czech Republic. uzhytchak@fzu.cz.
Anna LynnykInstitute of Physics of the Czech Academy of Sciences, 18221 Prague, Czech Republic. lynnyk@fzu.cz.
Šárka KubinováInstitute of Physics of the Czech Academy of Sciences, 18221 Prague, Czech Republic. sarka.k@biomed.cas.cz.
Alexandr DejnekaInstitute of Physics of the Czech Academy of Sciences, 18221 Prague, Czech Republic. dejneka@fzu.cz.ORCID 0000-0002-5116-8781
Oleg LunovInstitute of Physics of the Czech Academy of Sciences, 18221 Prague, Czech Republic. lunov@fzu.cz.ORCID 0000-0003-2922-8896

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physics-based biomedical approaches have proved their importance for the advancement of medical sciences and especially in medical diagnostics and treatments. Thus, the expectations regarding development of novel promising physics-based technologies and tools are very high. This review describes the latest research advances in biomedical applications of external physical cues. We overview three distinct topics: using high-gradient magnetic fields in nanoparticle-mediated cell responses; non-thermal plasma as a novel bactericidal agent; highlights in understanding of cellular mechanisms of laser irradiation. Furthermore, we summarize the progress, challenges and opportunities in those directions. We also discuss some of the fundamental physical principles involved in the application of each cue. Considerable technological success has been achieved in those fields. However, for the successful clinical translation we have to understand the limitations of technologies. Importantly, we identify the misconceptions pervasive in the discussed fields.

Indexed as

cell signalingcytotoxicitylasersmagnetic nanoparticlesnon-thermal plasma

Identifiers

PMID30586923
PMCPMC6463085

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.