SGLT2 inhibitors × adverse events & safety

SynthesisAnnals of internal medicine2019

Fracture Risk After Initiation of Use of Canagliflozin: A Cohort Study.

Michael Fralick et al.PubMed ↗Full text ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation · may be no link

No clear link with adverse events & safety

−8%−17% to +2%

Bigger than 3 in 10 for adverse events & safety

As reported

HR 0.92, 95% CI 0.83–1.02

One number in the abstract

the abstract, start to end

per 1000 person-years) (overall HR, 0.92 [CI, 0.83 to 1.02]).

← favours treatmentfavours comparator →
could be chance
Adverse events & safety
HR 0.920.83–1.02
SGLT2 inhibitorsAdverse events & safety
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