ArticleApplied health economics and health policy2019
The Association Between Adiposity and Inpatient Hospital Costs in the UK Biobank Cohort.
Article in Applied health economics and health policy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Blood DNA methylation of EIF5A and TGIF1 is associated with adipose tissue health and metabolic outcomes in obesity: a multi-cohort study.Clinical epigenetics · 2026Article
- Obesity, Physical Activity and Occurrence of High Medical Expenditures at One-Year Follow-Up Among Japanese Beneficiaries of Employment-Based Health Insurances: An Analysis Based on a Nationwide Health Checkup Questionnaire.Healthcare (Basel, Switzerland) · 2026Article
- Associations of Alzheimer's disease with inpatient hospital costs and with quality-adjusted life years: evidence from conventional and Mendelian randomization analyses in the UK Biobank.Cost effectiveness and resource allocation : C/E · 2025Article
- Mendelian Randomization Analysis of the Causal Effect of Cigarette Smoking on Hospital Costs.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- Causal Estimation of Long-term Intervention Cost-effectiveness Using Genetic Instrumental Variables: An Application to Cancer.Medical decision making : an international journal of the Society for Medical Decision Making · 2024Article
- Quantifying the causal impact of biological risk factors on healthcare costs.Nature communications · 2023Article
- Mendelian randomization analysis of the causal impact of body mass index and waist-hip ratio on rates of hospital admission.Economics and human biology · 2022Article
- Effects of adiposity on the human plasma proteome: observational and Mendelian randomisation estimates.International journal of obesity (2005) · 2021Observational
- Long-term cost-effectiveness of interventions for obesity: A mendelian randomisation study.PLoS medicine · 2021Article
- Mendelian randomization: estimation of inpatient hospital costs attributable to obesity.Health economics review · 2021Article
- Mendelian Randomization analysis of the causal effect of adiposity on hospital costs.Journal of health economics · 2020Article
- Uptake of direct oral anticoagulants in primary care: an ecological and economic study.BJGP open · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundHigh adiposity is associated with higher risks for a variety of adverse health outcomes, including higher rates of age-adjusted mortality and increased morbidity. This has important implications for the management of healthcare systems, since the endocrinal, cardiometabolic and other changes associated with increased adiposity may be associated with substantial healthcare costs.
methodsWe studied the association between various measures of adiposity and inpatient hospital costs through record linkage between UK Biobank and records of inpatient care in England and Wales. UK Biobank is a large prospective cohort study that aimed to recruit men and women aged between 40 and 69 from 2006 to 2010. We applied generalised linear models to cost per person year to estimate the marginal effect of adiposity, and average adjusted predicted costs of adiposity.
resultsValid cost and body mass index (BMI) data from 457,689 participants were available for inferential analysis. Some 54.4% of individuals included in the analysis sample had positive inpatient healthcare costs over the period of follow-up. Median hospital costs per person-year of follow-up were £89, compared to mean costs of £481. Mean BMI overall was 27.4 kg/m
conclusionsHigher adiposity is associated with higher inpatient hospital costs. Further scrutiny using causal inferential methods is warranted to establish if further public health investments are required to manage the large healthcare costs observationally associated with overweight and obesity.
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