Evidence map›Paper›PMID 30603891›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2021

Predictors of ventricular ablation's success: Viability, innervation, or mismatch?

Alessia Gimelli, Francesca Menichetti, Ezio Soldati, Riccardo Liga, Nicola Scelza, Giulio Zucchelli, Andrea Di Cori, Luca Segreti, Andrea Vannozzi, Maria Grazia Bongiorni and 1 more

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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Twenty-five years of research in cardiac imaging in electrophysiology procedures for atrial and ventricular arrhythmias.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  3. Anger recall mental stress decreasesJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Alessia GimelliFondazione Toscana G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy. gimelli@ftgm.it.
Francesca MenichettiCardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
Ezio SoldatiCardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
Riccardo LigaCardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
Nicola ScelzaCardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
Giulio ZucchelliCardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
Andrea Di CoriCardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
Luca SegretiCardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
Andrea VannozziCardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
Maria Grazia BongiorniCardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy.
Paolo MarzulloFondazione Toscana G. Monasterio, Via Moruzzi, 1, 56124, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsSympathetic dys-innervation may play an important role in the development of post-ischemic ventricular arrhythmias (VA). Aim of this study was to prove that perfusion/innervation mismatch (PIM) evaluated by SPECT can identify areas of local abnormal ventricular activities (LAVA) on electroanatomic mapping (EAM).

methodsSixteen patients referred to post-ischemic VA catheter ablation underwent pre-procedural and 1-month post-ablation

resultsBefore ablation, the mean voltage in the PIM segments was higher than in the scarred ones but lower than in the normal regions. The presence of PIM in a specific LV zone was an independent predictor of LAVA. After ablation, PIM value was significantly reduced, mainly due to an increase in perfusion summed rest score, in particular in patients that were responders to ablation.

conclusionsPIM may associate with VA substrate expressed by LAVA and might provide a novel guide for substrate ablation. A significant reduction of PIM could predict a positive clinical response to ablation.

Indexed as

Catheter Ablation3-IodobenzylguanidineAgedFemaleHeart VentriclesHumansMaleMiddle AgedMyocardial InfarctionOrganophosphorus CompoundsOrganotechnetium CompoundsPredictive Value of TestsRadiopharmaceuticalsRetrospective StudiesTachycardia, VentricularTomography, Emission-Computed, Single-Photon3-IodobenzylguanidineOrganophosphorus CompoundsOrganotechnetium CompoundsRadiopharmaceuticalstechnetium tc-99m tetrofosmincardiac innervationdiagnostic and prognostic applicationimage-guided applicationIntervention tracersmultimodality

Identifiers

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.