SynthesisJournal of nephrology2019
Incremental dialysis in ESRD: systematic review and meta-analysis.
Synthesis in Journal of nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05721404 (Icodextrin Postpones the Shift of Low Dose to Full Dose Dialysis in the First Year of Incremental Peritoneal Dialysis), which is not on this map. Cited by 57 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Icodextrin Postpones the Shift of Low Dose to Full Dose Dialysis in the First Year of Incremental Peritoneal Dialysis: A Randomized Controlled Trial
Who cites it
57 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A Meta-Analysis Examining the Impact of Consuming Nitrogen-Free Analogs of Essential Amino Acids on the Progression of Chronic Renal Disease.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Comparison of outcomes of incremental vs. standard peritoneal dialysis: a systematic review and meta-analysis.BMC nephrology · 2024Pooled it
- Impact of incremental initiation of haemodialysis on mortality: a systematic review and meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023Pooled it
- The Effect of Ketoanalogues on Chronic Kidney Disease Deterioration: A Meta-Analysis.Nutrients · 2019Pooled it
- Trial
- Ten tips for the first hemodialysis sessions.Clinical kidney journal · 2026Review
- Article
- Incremental Hemodialysis Practices and Impact on Survival: Systematic Review and Meta-Analysis.Kidney medicine · 2026Article
- Implementing a Protocol for Incremental Hemodialysis in Incident Patients With Kidney Failure: A Quality Improvement Initiative.Canadian journal of kidney health and disease · 2026Article
- Incremental vs. standard hemodialysis for preserving residual kidney function: a case-control study.BMC nephrology · 2025Observational
- Article
- Benefits and Challenges When Implementing Incremental Hemodialysis: A Qualitative Study of Patients and Providers.Canadian journal of kidney health and disease · 2025Article
- Incremental peritoneal dialysis: less is more-for the patient and the planet.Frontiers in medicine · 2025Review
- Redefining the concept of residual renal function with kidney sodium MRI: a pilot study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Observational
- Incremental hemodialysis and vascular access complications: a 12-year experience in a hospital hemodialysis unit.Journal of nephrology · 2024Article
- Personalized peritoneal dialysis prescription-beyond clinical or analytical values.Clinical kidney journal · 2024Article
- Shared decision making in elderly patients with kidney failure.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Review
- Eco-dialysis in Italy: where are we? National survey on the eco-sustainability of dialysis across Italian dialysis centers.Journal of nephrology · 2024Article
- The ability of phase angle and body composition to predict risk of death in maintenance hemodialysis patients.International urology and nephrology · 2024Article
- Incremental dialysis: two complementary views.Clinical kidney journal · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncremental dialysis may preserve residual renal function and improve survival in comparison with full-dose dialysis; however, available evidence is limited. We therefore compared all-cause mortality and residual kidney function (RKF) loss in incremental and full-dose dialysis and time to full-dose dialysis in incremental hemodialysis (IHD) and incremental peritoneal dialysis (IPD).
methodsWe performed a systematic review and meta-analysis of cohort studies of adults with ESRD starting IHD and IPD. We identified in PubMed and Web of Science database all cohort studies evaluating incremental dialysis evaluating three outcomes: all-cause mortality, RKF loss, time to full dialysis. IPD was defined as < 3 daily dwells in Continuous Ambulatory Peritoneal Dialysis and < 5 sessions per week in Automated Peritoneal Dialysis, while IHD was defined as < 3 HD sessions per week.
results22 studies (75,292 participants), 15 in HD and 7 in PD, were analyzed. Mean age at dialysis start was 62 and 57 years in IHD and IPD subjects, respectively. When compared to full dose, incremental dialysis (IHD or IPD) had an overall mortality risk of 1.14 [95% CI 0.85-1.52] with high heterogeneity among studies (I
conclusionsIncremental dialysis allows longer preservation of RKF thus deferring full-dose dialysis, by about 1 year in HD and PD, with no increase in mortality risk. Large and adequate studies are needed to confirm these findings.
Indexed as
Identifiers
30604150What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.