Evidence mapPaperPMID 30617701Full record

ReviewDer Internist2019

[Glucose metabolism in older patients].

T Laurentius, M Freitag, J Eitner, A Eisert, T Bertsch, L C Bollheimer

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Internist, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

T LaurentiusLehrstuhl für Altersmedizin, Klinik für Innere Medizin und Geriatrie am Franziskushospital Aachen, Uniklinik RWTH Aachen, Morillenhang 27, 52074, Aachen, Deutschland.
M FreitagLehrstuhl für Altersmedizin, Klinik für Innere Medizin und Geriatrie am Franziskushospital Aachen, Uniklinik RWTH Aachen, Morillenhang 27, 52074, Aachen, Deutschland.
J EitnerLehrstuhl für Altersmedizin, Klinik für Innere Medizin und Geriatrie am Franziskushospital Aachen, Uniklinik RWTH Aachen, Morillenhang 27, 52074, Aachen, Deutschland.
A EisertApotheke, Uniklinik RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Deutschland.
T BertschInstitut für Klinische Chemie, Laboratoriumsmedizin und Transfusionsmedizin, Klinikum Nürnberg, Paracelsus Medizinische Privatuniversität, Professor-Ernst-Nathan-Straße 1, 90419, Nürnberg, Deutschland.
L C BollheimerLehrstuhl für Altersmedizin, Klinik für Innere Medizin und Geriatrie am Franziskushospital Aachen, Uniklinik RWTH Aachen, Morillenhang 27, 52074, Aachen, Deutschland. cbollheimer@ukaachen.de.
Franziskushospital Aachen · DEUniversitätsklinikum Aachen · DENuremberg Hospital · DERWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current guidelines for specialized treatment of diabetes mellitus in the elderly (>65 years old) are primarily based on epidemiologic studies and geriatric assessment of functional health. Yet, age-dependent alterations of glucose metabolism and homeostasis are highly relevant to the pathophysiology of diabetes in the elderly. In this review, we focus on age-related alterations in metabolic pathways and their relevance for the specialized diabetic care in the elderly. We review the role of increasing insulin resistance, age-related β‑cell dysfunction and incretin secretion. The clinical relevance of these effects will also be discussed in regard to the central geriatric syndrome of sarcopenia and antidiabetic drug therapy.

Indexed as

Insulin ResistanceSarcopeniaAgedAgingBlood GlucoseDiabetes Mellitus, Type 2GlucoseHumansHypoglycemic AgentsInsulinMuscle ProteinsBlood GlucoseGlucoseHypoglycemic AgentsInsulinMuscle ProteinsAgingDiabetes mellitusInsulin resistanceInsulin-secreting cellsSarcopenia

Identifiers

PMID30617701
OpenAlexW2909292747

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.