Evidence map›Paper›PMID 30622227›Full record

ArticleMolecules and cells2019

HeLa E-Box Binding Protein, HEB, Inhibits Promoter Activity of the Lysophosphatidic Acid Receptor Gene

Nam-Ho Kim, Ali Sadra, Hee-Young Park, Sung-Min Oh, Jerold Chun, Jeong Kyo Yoon, Sung-Oh Huh

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules and cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Nam-Ho KimDepartment of Pharmacology, College of Medicine, Institute of Natural Medicine, Hallym University, Chuncheon 24252, Korea.
Ali SadraDepartment of Pharmacology, College of Medicine, Institute of Natural Medicine, Hallym University, Chuncheon 24252, Korea.
Hee-Young ParkDepartment of Pharmacology, College of Medicine, Institute of Natural Medicine, Hallym University, Chuncheon 24252, Korea.
Sung-Min OhDepartment of Pharmacology, College of Medicine, Institute of Natural Medicine, Hallym University, Chuncheon 24252, Korea.
Jerold ChunSanford Burnham Prebys Medical Discovery Institute, CA 92037, USA.
Jeong Kyo YoonSoonchunhyang Institute of Medi-Bio Science, Soonchunhyang University, Asan 31538, Korea.
Sung-Oh HuhDepartment of Pharmacology, College of Medicine, Institute of Natural Medicine, Hallym University, Chuncheon 24252, Korea.
Hallym University · KRDiscovery Institute · USSoonchunhyang University · KR

Funding

Prenatal blood-borne lipids in post-hemorrhagic hydrocephalusR01NS084398 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI CHUN, JEROLD · 2014 to 2017
$2.6M
NINDS NIH HHS R01 NS084398
6 · The paper itself

Abstract

Lysophosphatidic acid (LPA) is an endogenous lysophospholipid with signaling properties outside of the cell and it signals through specific G protein-coupled receptors, known as LPA

Indexed as

Promoter Regions, Genetic5' Flanking RegionAnimalsBase SequenceBasic Helix-Loop-Helix ProteinsE-Box ElementsGene Expression RegulationHeLa CellsHumansMiceNeocortexNeuronsProtein BindingReceptors, Lysophosphatidic AcidSequence DeletionTranscription Initiation SiteBasic Helix-Loop-Helix ProteinsReceptors, Lysophosphatidic AcidTcf12 protein, mousealternative splicingHeLa E-box binding proteinlysophosphatidic acid receptor 1transcription repressor

Identifiers

PMID30622227
PMCPMC6399008
OpenAlexW2982127936

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.