Evidence map›Paper›PMID 30626734›Full record

ReviewThe Journal of biological chemistry2019

Nutrient regulation of signaling and transcription.

Gerald W Hart

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 201 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
201citing papers in PubMed, 1 pooled it
60.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

201 citing papers in PubMed, 1 synthesis or guideline pooled it, 349 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Liver Stiffness Characterization of OGTJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  6. Article
  7. Glucosamine as a regulator of O-GlcNAc signaling: linking metabolism to disease pathogenesis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  8. Article
  9. Post-Translational Modifications in Animal Circadian Clocks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  10. Article
  11. Glycan-related genes and genetic disorders.Journal of human genetics · 2026
    Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. December In focus in HCB.Histochemistry and cell biology · 2025
    Article
  17. Review
  18. Review
  19. Article
  20. Article

141 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Gerald W HartFrom the Complex Carbohydrate Research Center and Biochemistry and Molecular Biology Department, University of Georgia, Athens, Georgia 30602 gerald.hart@uga.edu.
University of Georgia · US

Funding

Shared Resource CoresP01HL107153 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ZHANG, HUI · 2011 to 2017
$16.8M
Cytosolic O-Glycosylation and Insulin SignalingR01DK061671 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI HART, GERALD WARREN · 2002 to 2014
$4.0M
Nutrient Regulation of Cell Physiology by O-GlcNAcylationR01GM116891 · NIGMS · UNIVERSITY OF GEORGIA · PI HART, GERALD WARREN · 2016 to 2023
$2.4M
NHLBI NIH HHS P01 HL107153NIDDK NIH HHS R01 DK061671NIGMS NIH HHS R01 GM116891
6 · The paper itself

Abstract

In the early 1980s, while using purified glycosyltransferases to probe glycan structures on surfaces of living cells in the murine immune system, we discovered a novel form of serine/threonine protein glycosylation (

Indexed as

Signal TransductionTranscription, GeneticAgingAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsChronic DiseaseCytoskeletonDiabetes MellitusGlycosylationHumansMiceMitochondriaN-AcetylglucosaminyltransferasesNeoplasm ProteinsNeoplasmsCaenorhabditis elegans ProteinsN-AcetylglucosaminyltransferasesNeoplasm ProteinsNutrientsAlzheimer's diseasecancerdiabeteskinasesneurodegenerationO-GlcNAcaseO-GlcNAcylationO-linked N-acetylglucosamine (O-GlcNAc)O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT)phosphorylation

Identifiers

PMID30626734
PMCPMC6378989
OpenAlexW2911143204

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.