Evidence map›Paper›PMID 30626781›Full record

ArticleJournal of atherosclerosis and thrombosis2019

Shape and Location of Carotid Atherosclerotic Plaque and Intraplaque Hemorrhage: A High-resolution Magnetic Resonance Imaging Study.

Mingming Lu, Yuanyuan Cui, Peng Peng, Huiyu Qiao, Jianming Cai, Xihai Zhao

Open access · diamondAbstract read
In one paragraph

Article in Journal of atherosclerosis and thrombosis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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  13. HR-MRI findings of intracranial artery stenosis and distribution of atherosclerotic plaques caused by different etiologies.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Mingming LuDepartment of Radiology, PLA General Hospital.
Yuanyuan CuiDepartment of Radiology, PLA General Hospital.
Peng PengDepartment of Radiology, Pingjin Hospital, Logistics University of Chinese People's Armed Police Forces.
Huiyu QiaoCenter for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University School of Medicine.
Jianming CaiDepartment of Radiology, PLA General Hospital.
Xihai ZhaoCenter for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University School of Medicine.
Chinese PLA General Hospital · CNTsinghua University · CNLogistics University of People's Armed Police Force · CNPingjin Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe present study aimed to investigate the association between shape and location of atherosclerotic plaques and intraplaque hemorrhage (IPH) in carotid arteries using magnetic resonance (MR) imaging.

methodsOverall, 114 symptomatic patients (mean age: 64.9±10.9 years; 81 males) who underwent MR imaging and had advanced carotid plaques were included in analysis. IPH presence and carotid plaque shape and location (below and above bifurcation) were evaluated. The plaque shape was defined as follows: type-I: the arc-length of plaque is greater in the upstream; type-II: the arc-length of plaque in downstream and upstream is equal; and type-III: the arc-length of plaque is greater in downstream. The plaque shape and location were compared between plaques with and without IPH and their associations with IPH were determined.

resultsOf 181detectedplaques, 57 (31.5%) had IPH. Compared with plaques without IPH, those with IPH had higher incidence of the plaque shape of type-I (66.7% vs. 32.2%, P<0.001), lower incidence of plaque shape of type-III (24.6% vs. 50.0%, P=0.001), and were more likely located above carotid bifurcation (71.9% vs. 48.4%, P=0.003). The plaque shape of type-I (OR, 4.01; 95%CI, 1.36-11.83; P=0.012) and location above bifurcation (OR, 3.21; 95%CI, 1.07-9.61; P=0.037) of carotid plaques were significantly associated with IPH after adjusting for confounder factors.

conclusionsCarotid plaque shape and location are significantly associated with the occurrence of IPH. Our findings could provide new insights for the pathogenesis of IPH and vulnerably plaques.

Indexed as

AgedCarotid ArteriesCoronary Artery DiseaseFemaleFollow-Up StudiesHemorrhageHumansMagnetic Resonance ImagingMaleMiddle AgedPlaque, AtheroscleroticPrognosisAtherosclerosisCarotid arteryIntraplaque hemorrhageMagnetic resonance imagingRisk factor

Identifiers

PMID30626781
PMCPMC6711842
OpenAlexW2908669040

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.