Evidence map›Paper›PMID 30634637›Full record

ReviewPharmaceuticals (Basel, Switzerland)2019

The Therapeutic Potential of Naringenin: A Review of Clinical Trials.

Bahare Salehi, Patrick Valere Tsouh Fokou, Mehdi Sharifi-Rad, Paolo Zucca, Raffaele Pezzani, Natália Martins, Javad Sharifi-Rad

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05618483 (Clinical Efficacy of Xylitol Based Nasal Spray for the Treatment of Mild COVID-19 Infection), which is not on this map. Cited by 315 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
315citing papers in PubMed, 5 pooled it
30.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05618483 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Clinical Efficacy of Xylitol Based Nasal Spray for the Treatment of Mild COVID-19 Infection

TypeinterventionalSponsorXlear, IncRan2022 to 2024Enrolled80ConditionsRespiratory Viral InfectionArmsNasal Spray
3 · Its place in the literature

Who cites it

315 citing papers in PubMed, 5 syntheses or guidelines pooled it, 771 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Antioxidant and Anti-Aging Activity ofMolecules (Basel, Switzerland) · 2026
    Article
  16. Trypanocidal Activity of Crude Extracts fromJournal of fungi (Basel, Switzerland) · 2026
    Article
  17. Chinese herbal medicines · 2026
    Review
  18. Article
  19. Review
  20. Article

255 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

Bahare SalehiStudent Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran. bahar.salehi007@gmail.com.ORCID 0000-0002-6900-9797
Patrick Valere Tsouh FokouAntimicrobial and Biocontrol Agents Unit, Department of Biochemistry, Faculty of Science, University of Yaounde 1, Ngoa Ekelle, Annex Fac. Sci., Yaounde 812, Cameroon. tsouh80@yahoo.fr.ORCID 0000-0003-3724-3527
Mehdi Sharifi-RadDepartment of Medical Parasitology, Zabol University of Medical Sciences, Zabol 61663-335, Iran. m.sharifirad@zbmu.ac.ir.
Paolo ZuccaDepartment of Biomedical Sciences, University of Cagliari, 09042 Cagliari, Italy. pzucca@unica.it.ORCID 0000-0002-3548-7635
Raffaele PezzaniOU Endocrinology, Dept. Medicine (DIMED), University of Padova, via Ospedale 105, 35128 Padova, Italy. raffaele.pezzani@unipd.it.ORCID 0000-0003-3156-2500
Natália MartinsFaculty of Medicine, University of Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal. ncmartins@med.up.pt.ORCID 0000-0002-5934-5201
Javad Sharifi-RadZabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol 61615585, Iran. javad.sharifirad@gmail.com.ORCID 0000-0002-7301-8151
Zabol University of Medical Sciences · IRBam University of Medical Sciences · IRUniversidade do Porto · PTUniversité de Yaoundé I · CMUniversity of Cagliari · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naringenin is a flavonoid belonging to flavanones subclass. It is widely distributed in several

Indexed as

cardiovascular diseaseschemopreventivecitrusflavanonesflavonoidsnutraceuticsphytochemicals

Identifiers

PMID30634637
PMCPMC6469163
OpenAlexW2908708255

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.