Evidence map›Paper›PMID 30649199›Full record

ArticleBioinformatics (Oxford, England)2019

EBIC: an open source software for high-dimensional and big data analyses.

Patryk Orzechowski, Jason H Moore

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biclustering data analysis: a comprehensive survey.Briefings in bioinformatics · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Patryk OrzechowskiInstitute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA, USA.
Jason H MooreInstitute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

motivationIn this paper, we present an open source package with the latest release of Evolutionary-based BIClustering (EBIC), a next-generation biclustering algorithm for mining genetic data. The major contribution of this paper is adding a full support for multiple graphics processing units (GPUs) support, which makes it possible to run efficiently large genomic data mining analyses. Multiple enhancements to the first release of the algorithm include integration with R and Bioconductor, and an option to exclude missing values from the analysis.

resultsEvolutionary-based BIClustering was applied to datasets of different sizes, including a large DNA methylation dataset with 436 444 rows. For the largest dataset we observed over 6.6-fold speedup in computation time on a cluster of eight GPUs compared to running the method on a single GPU. This proves high scalability of the method. AVAILABILITY AND IMPLEMENTATION: The latest version of EBIC could be downloaded from http://github.com/EpistasisLab/ebic. Installation and usage instructions are also available online. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Data AnalysisSoftwareAlgorithmsDNA MethylationGenomics

Identifiers

PMID30649199
PMCPMC6736067

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.