Evidence mapPaperPMID 30659434Full record

Trial reportAnnals of biomedical engineering2019

Prediction of Long Term Restenosis Risk After Surgery in the Carotid Bifurcation by Hemodynamic and Geometric Analysis.

Maurizio Domanin, Diego Gallo, Christian Vergara, Pietro Biondetti, Laura V Forzenigo, Umberto Morbiducci

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Annals of biomedical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Modeling Hemodynamic Effects of the Closure Procedure of Carotid Artery Endarterectomy.International journal for numerical methods in biomedical engineering · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Carotid Endarterectomy.Advances and technical standards in neurosurgery · 2022
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Maurizio Domanin *Department of Clinical Sciences and Community Health, Università di Milano, Milan, Italy.
Diego Gallo *PolitoBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Christian VergaraLaboratory of Biological Structure Mechanics (LaBS), Dipartimento di Chimica, Materiali e Ingegneria Chimica "Giulio Natta", Politecnico di Milano, Milan, Italy.
Pietro BiondettiUnità Operativa di Radiologia, Fondazione I.R.C.C.S. Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
Laura V ForzenigoUnità Operativa di Radiologia, Fondazione I.R.C.C.S. Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
Umberto MorbiducciPolitoBIOMed Lab, Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy. umberto.morbiducci@polito.it.ORCID http://orcid.org/0000-0002-9854-1619
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITPolitecnico di Torino · ITPolitecnico di Milano · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explored the potential of hemodynamic disturbances and geometric features to predict long-term carotid restenosis after carotid endarterectomy (CEA). Thirteen CEA for carotid diameter stenosis > 70% were performed with patch graft (PG) angioplasty in nine cases, and primary closure (PC) in four cases. MRI acquisitions within one month after CEA were used for hemodynamic and geometric characterization. Personalized computational hemodynamic simulations quantified the exposure to low and oscillatory wall shear stress (WSS). Geometry was characterized in terms of flare (the expansion at the bulb) and tortuosity. At 60 months after CEA, Doppler ultrasound (DUS) was applied for restenosis detection and intima-media thickness determination. Larger flares were associated to larger exposure to low WSS (Pearson R

Indexed as

Carotid Artery, InternalCarotid Intima-Media ThicknessCarotid StenosisEndarterectomy, CarotidModels, CardiovascularShear StrengthAgedAged, 80 and overFemaleHumansMaleMiddle AgedPredictive Value of TestsRecurrenceRisk FactorsCarotid endarterectomyComputational fluid dynamicsFlareRecurrent stenosisTortuosityWall shear stress

Identifiers

PMID30659434
OpenAlexW2910653041

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.