Evidence map›Paper›PMID 30660638›Full record

Trial reportThe Journal of allergy and clinical immunology2019

Gamma tocopherol effect on LPS-induced sputum neutrophilia is not modified by BMI or GSTM1 genotype.

Amika K Sood, Allison J Burbank, Charity G Duran, Kimberly Enders, Haibo Zhou, David B Peden, Michelle L Hernandez

Open access · greenAbstract readLetterRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of allergy and clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Amika K SoodCenter for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina, Chapel Hill, NC; Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of North Carolina, Chapel Hill, NC. Electronic address: amika_sood@med.unc.edu.
Allison J BurbankCenter for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina, Chapel Hill, NC; Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of North Carolina, Chapel Hill, NC.
Charity G DuranCenter for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina, Chapel Hill, NC.
Kimberly EndersDepartment of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC.
Haibo ZhouCenter for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina, Chapel Hill, NC; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC.
David B PedenCenter for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina, Chapel Hill, NC; Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of North Carolina, Chapel Hill, NC.
Michelle L HernandezCenter for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina, Chapel Hill, NC; Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of North Carolina, Chapel Hill, NC.
University of North Carolina at Chapel Hill · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
UNC-Duke Collaborative Clinical Pharmacology Postdoctoral Training Program-Evaluation SupplementT32GM086330 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KIM L.R. BROUWER, Daniel Gonzalez · 2011 to 2026
$8.5M
RESEARCH TRAINING IN ALLERGY AND CLINICAL IMMUNOLOGYT32AI007062 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David B. Peden, John W. Sleasman · 1985 to 2026
$6.1M
Phase II studies of gamma tocopherol as an intervention for environmental asthmaR01ES023349 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PEDEN, DAVID B. · 2013 to 2017
$3.7M
Gamma tocopherol chemoprevention of wood smoke PM2.5-induced airway inflammationR01ES025124 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PEDEN, DAVID B. · 2016 to 2020
$2.8M
IL-1 receptor blockade as a novel treatment for exacerbation of allergic airway responses in humansR01HL135235 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HERNANDEZ, MICHELLE · 2017 to 2021
$2.7M
Down-regulation of oxidant-induced airway inflammation though modulation of NRF2K23ES021745 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HERNANDEZ, MICHELLE · 2012 to 2014
$612k
NHLBI NIH HHS R01 HL135235NIAID NIH HHS T32 AI007062NIEHS NIH HHS K23 ES021745NIEHS NIH HHS P30 ES010126NIEHS NIH HHS R01 ES023349NIEHS NIH HHS R01 ES025124NIGMS NIH HHS T32 GM086330
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Body Mass IndexAdultCross-Over StudiesDouble-Blind MethodFemalegamma-TocopherolGenotypeGlutathione TransferaseHumansLipopolysaccharidesMaleMiddle AgedNeutrophilsSputumYoung Adultgamma-TocopherolGlutathione TransferaseLipopolysaccharides

Identifiers

PMID30660638
PMCPMC6504592
OpenAlexW2909695409

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.