ArticleJournal of ginseng research2019
Label-free quantitative proteomic analysis of
Article in Journal of ginseng research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 33 citations in OpenAlex.
- Deciphering the PgLEA2-50 interactome: implications for abiotic stress responses inPlant signaling & behavior · 2026Article
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- A Heat-Shock Transcription Factor inInternational journal of molecular sciences · 2025Article
- Plant stress and proteomics in medicinal plants.Frontiers in plant science · 2025Review
- From single- to multi-omics: future research trends in medicinal plants.Briefings in bioinformatics · 2023Article
- Exogenous leucine alleviates heat stress and improves saponin synthesis inFrontiers in plant science · 2023Article
- Molecular analysis of thePeerJ · 2023Article
- Prolonged Exposure to High Temperature Inhibits Shoot Primary and Root Secondary Growth inInternational journal of molecular sciences · 2022Article
- High-Throughput Phenotyping Approach for the Evaluation of Heat Stress in Korean Ginseng (Sensors (Basel, Switzerland) · 2021Article
- Optimization of Protein Isolation and Label-Free Quantitative Proteomic Analysis in Four Different Tissues of Korean Ginseng.Plants (Basel, Switzerland) · 2021Article
- Spatial protein expression ofJournal of ginseng research · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGinseng is one of the well-known medicinal plants, exhibiting diverse medicinal effects. Its roots possess anticancer and antiaging properties and are being used in the medical systems of East Asian countries. It is grown in low-light and low-temperature conditions, and its growth is strongly inhibited at temperatures above 25°C. However, the molecular responses of ginseng to heat stress are currently poorly understood, especially at the protein level.
methodsWe used a shotgun proteomics approach to investigate the effect of heat stress on ginseng leaves. We monitored their photosynthetic efficiency to confirm physiological responses to a high-temperature stress.
resultsThe results showed a reduction in photosynthetic efficiency on heat treatment (35°C) starting at 48 h. Label-free quantitative proteome analysis led to the identification of 3,332 proteins, of which 847 were differentially modulated in response to heat stress. The MapMan analysis showed that the proteins with increased abundance were mainly associated with antioxidant and translation-regulating activities, whereas the proteins related to the receptor and structural-binding activities exhibited decreased abundance. Several other proteins including chaperones, G-proteins, calcium-signaling proteins, transcription factors, and transfer/carrier proteins were specifically downregulated.
conclusionThese results increase our understanding of heat stress responses in the leaves of ginseng at the protein level, for the first time providing a resource for the scientific community.
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