Evidence map›Paper›PMID 30669405›Full record

ReviewMolecules (Basel, Switzerland)2019

Peptides for Skin Protection and Healing in Amphibians.

Ilaria Demori, Zeinab El Rashed, Viola Corradino, Annamaria Catalano, Leila Rovegno, Linda Queirolo, Sebastiano Salvidio, Emanuele Biggi, Matteo Zanotti-Russo, Laura Canesi and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Skin Histology ofAntioxidants (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Ilaria DemoriDipartimento Scienze della Terra dell'Ambiente e della Vita ⁻DISTAV, Università degli Studi di Genova ⁻ 16132 Genova, Italy. idemori@unige.it.
Zeinab El RashedDipartimento Scienze della Terra dell'Ambiente e della Vita ⁻DISTAV, Università degli Studi di Genova ⁻ 16132 Genova, Italy. Zeinab.ALRashed94@hotmail.com.
Viola CorradinoDipartimento Scienze della Terra dell'Ambiente e della Vita ⁻DISTAV, Università degli Studi di Genova ⁻ 16132 Genova, Italy. violacorradino@outlook.it.
Annamaria CatalanoiDelivery iSrl, Via Eremo al Santuario n.75/A, 89124 Reggio Calabria, Italy. catalano@idelivery.it.
Leila RovegnoDipartimento Scienze della Terra dell'Ambiente e della Vita ⁻DISTAV, Università degli Studi di Genova ⁻ 16132 Genova, Italy. leila.rovegno@gmail.com.
Linda QueiroloDipartimento Scienze della Terra dell'Ambiente e della Vita ⁻DISTAV, Università degli Studi di Genova ⁻ 16132 Genova, Italy. queirolo.linda@gmail.com.
Sebastiano SalvidioDipartimento Scienze della Terra dell'Ambiente e della Vita ⁻DISTAV, Università degli Studi di Genova ⁻ 16132 Genova, Italy. salvidio@dipteris.unige.it.
Emanuele BiggiInternational League of Conservation Photographers, Arlington, VA 22203, USA. ebiggi@anura.it.
Matteo Zanotti-RussoAngel Consulting via San Senatore 14, 20122 Milano, Italy. info@angelconsulting.eu.
Laura CanesiDipartimento Scienze della Terra dell'Ambiente e della Vita ⁻DISTAV, Università degli Studi di Genova ⁻ 16132 Genova, Italy. laura.canesi@unige.it.
Alessandro CatenazziDepartment of Biological Sciences, Florida International University, Miami, FL 33199, USA. acatenazzi@gmail.com.ORCID 0000-0002-3650-4783
Elena GrasselliDipartimento Scienze della Terra dell'Ambiente e della Vita ⁻DISTAV, Università degli Studi di Genova ⁻ 16132 Genova, Italy. elena.grasselli@unige.it.ORCID 0000-0003-4439-4059
University of Genoa · ITConservation International · USFlorida International University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amphibian skin is not to be considered a mere tegument; it has a multitude of functions related to respiration, osmoregulation, and thermoregulation, thus allowing the individuals to survive and thrive in the terrestrial environment. Moreover, amphibian skin secretions are enriched with several peptides, which defend the skin from environmental and pathogenic insults and exert many other biological effects. In this work, the beneficial effects of amphibian skin peptides are reviewed, in particular their role in speeding up wound healing and in protection from oxidative stress and UV irradiation. A better understanding of why some species seem to resist several environmental insults can help to limit the ongoing amphibian decline through the development of appropriate strategies, particularly against pathologies such as viral and fungal infections.

Indexed as

Amino Acid SequenceAmphibiansAnimalsAntioxidantsExocrine GlandsFree Radical ScavengersHumansPeptidesProtective AgentsSkinUltraviolet RaysWound HealingAntioxidantsFree Radical ScavengersPeptidesProtective Agentsamphibian skin peptidesanimal physiologyBatracochytrium dendrobatidiseco-physiologykeratinized tegumentskin defensesUV-irradiation protectionwound healing

Identifiers

PMID30669405
PMCPMC6359409
OpenAlexW2909234725

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.