ArticleLipids1988
Lipid composition of normal male rat islets.
Article in Lipids, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- High Spatial Resolution Imaging of Mouse Pancreatic Islets Using Nanospray Desorption Electrospray Ionization Mass Spectrometry.Analytical chemistry · 2018Article
- The role of rapid lipogenesis in insulin secretion: Insulin secretagogues acutely alter lipid composition of INS-1 832/13 cells.Archives of biochemistry and biophysics · 2008Article
- Lipid composition of glucose-stimulated pancreatic islets and insulin-secreting tumor cells.Lipids · 1994Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lipid composition was studied in fresh isolated islets from normal male rats. Extractable lipids represent 1856 micrograms per mg islet protein. In such extracts, phospholipids and neutral lipids represent 13.5% and 86.5%, respectively. Phosphatidylcholine (45.8%) and phosphatidylethanolamine (20.6%) were the major components of the phospholipid fraction, and phosphatidylinositol (8.9%) was the minor component. Esterified cholesterol (38.5%), cholesterol (25.5%) and free fatty acids (24.4%) were the major components of the neutral lipid fraction. Fatty acids esterified to phospholipids account for 619.7 pmol/islet, and 2710 pmol/islet were esterified to neutral lipids. In the phospholipid fraction, saturated and unsaturated fatty acids were in a similar proportion. Conversely, in the neutral lipids, two-thirds of the fatty acids were unsaturated. The omega 6 family was the main component of the phospholipid unsaturated fatty acids. In the omega 6 and omega 3 families, the long-chain fatty acids represent the main components. In the neutral lipid fraction, a different percentage of each family was found: omega 3 greater than omega 6 greater than omega 9. The long-chain polyunsaturated fatty acids were also predominant species in the omega 6 and omega 3 families. Further studies on the lipid composition of islets, obtained from rats with normal and altered islet functions, could provide new insights into the knowledge of the mechanism of insulin secretion.
Indexed as
Identifiers
3067021What Socratic holds
Registered trials
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