Evidence map›Paper›PMID 30670616›Full record

ArticlemBio2019

Effects of Friend Virus Infection and Regulatory T Cells on the Antigen Presentation Function of B Cells.

Tyler C Moore, Ronald J Messer, Lorena M Gonzaga, Jennifer M Mather, Aaron B Carmody, Wibke Bayer, Elisabeth Littwitz-Salomon, Ulf Dittmer, Kim J Hasenkrug

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Cytotoxic CD4Frontiers in immunology · 2023
    Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Tyler C MooreLaboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Ronald J MesserLaboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Lorena M GonzagaLaboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Jennifer M MatherLaboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Aaron B CarmodyResearch Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA.
Wibke BayerInstitute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.ORCID 0000-0002-5885-5592
Elisabeth Littwitz-SalomonInstitute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Ulf DittmerInstitute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Kim J HasenkrugLaboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA khasenkrug@nih.gov.ORCID 0000-0001-8523-4911
National Institutes of Health · USUniversity of Duisburg-Essen · DE

Funding

Immunology And Pathology Of Acute Murine Leukemia Virus InfectionsZIAAI000753 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI HASENKRUG, KIM · 2009 to 2022
$8.1M
6 · The paper itself

Abstract

Friend virus (FV) is a naturally occurring mouse retrovirus that infects dividing cells of the hematopoietic lineage, including antigen-presenting cells (APCs). The infection of APCs by viruses often induces their dysfunction, and it has been shown that FV infection reduces the ability of dendritic cells (DCs) to prime critical CD8

Indexed as

Antigen PresentationAnimalsB7-1 AntigenB7-2 AntigenB-LymphocytesCD40 AntigensCD8-Positive T-LymphocytesCell ProliferationFriend murine leukemia virusHistocompatibility Antigens Class IILeukemia, ExperimentalLymphocyte ActivationMiceRetroviridae InfectionsT-Lymphocytes, RegulatoryTumor Virus InfectionsB7-1 AntigenB7-2 AntigenCD40 AntigensHistocompatibility Antigens Class IIantigen presentationB-cell responsesCD8+ T cellsregulatory T cellsretroviruses

Identifiers

PMID30670616
PMCPMC6343038
OpenAlexW2912869580

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.