ReviewJournal of toxicology2018
A Review of Metal Exposure and Its Effects on Bone Health.
Review in Journal of toxicology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
83 citing papers in PubMed, 238 citations in OpenAlex.
- Circulating Elements in the Bloodstream of Growing Foals: Focus on Heavy Metals and Bone Remodeling Across Growth Stages.Biological trace element research · 2026Article
- Chronic developmental exposure to traffic-derived PMScientific reports · 2026Article
- Association between blood lead levels and body composition parameters in middle-aged pre- and postmenopausal women.BMC public health · 2026Article
- Metallic Contaminants and Osteoporosis: a Review of the Gut-Bone Axis.Biological trace element research · 2026Review
- Geochemical tales of individual lives in the industrial revolution: Untangling the impact of pollutant exposure in two English towns.Science advances · 2025Article
- The Protective Effect of Zinc Supplementation Against Oxidative Stress and Oxidative Modifications of Cellular Macromolecules in the Mandibular Bone of Rats Exposed to Cadmium.Antioxidants (Basel, Switzerland) · 2025Article
- Review of the anatomical basis for predicting plutonium alpha particle radiation induced osteogenic cancers.Anatomical record (Hoboken, N.J. : 2007) · 2025Review
- pXRF Skeletal Measurements as an Assessment Tool for Environmental Exposure to Lajes Field-Derived Contaminants (Terceira Island, Azores, Portugal).Biological trace element research · 2025Article
- Impact of Maternal Exposure to Trace Metal Mixtures on Bone Mineral Density in Children Aged 3-6: Results from the Guangxi Zhuang Birth Cohort, China.Biological trace element research · 2025Article
- Women's bone health trajectories from pregnancy to postpartum: Associations with bone-seeking metal exposure mixtures during pregnancy.Ecotoxicology and environmental safety · 2025Article
- Trace Elements-Role in Joint Function and Impact on Joint Diseases.International journal of molecular sciences · 2025Review
- The association between occupational lead exposure and serum levels of vitamin D3 and a bone turnover biomarker in smelter workers.International archives of occupational and environmental health · 2025Article
- The Impact of Fermented Dairy Products and Probiotics on Bone Health Improvement.Food science of animal resources · 2025Review
- Rethinking Biomedical Titanium Alloy Design: A Review of Challenges from Biological and Manufacturing Perspectives.Advanced healthcare materials · 2025Review
- How In Vivo Alteration of Hip Replacement Wear Mode Can Cause a Voluminous Inflammatory Reaction and an Excessive Titanium Exposure.Journal of clinical medicine · 2025Article
- Elemental imbalance and oxidative biomarker shifts in lumbar disc degeneration.Frontiers in neurology · 2025Article
- Predictive Modeling of Osteoarthritis Using Biochemical Markers: A Cross-Sectional Analysis.Journal of orthopaedic case reports · 2024Article
- Article
- Lead Concentrations in Tissues of Pigeons (Toxics · 2024Article
- Synthesis of High-Purity Hydroxyapatite and Phosphoric Acid Derived from Moroccan Natural Phosphate Rocks by Minimizing Cation Content Using Dissolution-Precipitation Technique.Molecules (Basel, Switzerland) · 2024Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The presence of metals in the environment is a matter of concern, since human activities are the major cause of pollution and metals can enter the food chain and bioaccumulate in hard and soft tissues/organs, which results in a long half-life of the metal in the body. Metal intoxication has a negative impact on human health and can alter different systems depending on metal type and concentration and duration of metal exposure. The present review focuses on the most common metals found in contaminated areas (cadmium, zinc, copper, nickel, mercury, chromium, lead, aluminum, titanium, and iron, as well as metalloid arsenic) and their effects on bone tissue. Both the lack and excess of these metals in the body can alter bone dynamics. Long term exposure and short exposure to high concentrations induce an imbalance in the bone remodeling process, altering both formation and resorption and leading to the development of different bone pathologies.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.