ArticleMolecular systems biology2019
Widespread inter-individual gene expression variability in
Article in Molecular systems biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 81 citations in OpenAlex.
- Inter-individual gene expression variability implies stable regulation of brain-biased genes across organs in three ray-finned fishes.bioRxiv : the preprint server for biology · 2026Article
- Dynamics of Expression Variability Contribute to Retention of Small-Scale vs. Whole-Genome Duplicates.Genome biology and evolution · 2026Article
- Environmental perturbation increases gene expression variability and unmasks genetic regulation for transcriptional robustness.bioRxiv : the preprint server for biology · 2026Article
- Gene body methylation buffers noise in gene expression in plants.Nucleic acids research · 2026Article
- GEAR: an integrated atlas of gene expression dynamics in Arabidopsis thaliana.Nucleic acids research · 2026Article
- A non-destructive plant screening method for improving sample uniformity in horticultural crops based on a hydrogen peroxide fluorescent probe.Frontiers in plant science · 2026Article
- Establishment and maintenance of NRT2.1 inter-individual variability in plants.PLoS genetics · 2025Article
- Highly expressed cell wall genes contribute to robustness of sepal size.Plant signaling & behavior · 2025Article
- Building resilience by cultivating difference: A role for noise in development.Current opinion in plant biology · 2025Review
- Machine learning models highlight environmental and genetic factors associated with the Arabidopsis circadian clock.Nature communications · 2025Article
- Phenotype prediction in plants is improved by integrating large-scale transcriptomic datasets.NAR genomics and bioinformatics · 2024Article
- Single-plant-omics reveals the cascade of transcriptional changes during the vegetative-to-reproductive transition.The Plant cell · 2024Article
- Bet-hedging and variability in plant development: seed germination and beyond.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Genetically encoded transcriptional plasticity underlies stress adaptation in Mycobacterium tuberculosis.Nature communications · 2024Article
- Anthracyclines induce cardiotoxicity through a shared gene expression response signature.PLoS genetics · 2024Article
- Getting it right: suppression and leveraging of noise in robust decision-making.Quantitative plant biology · 2024Review
- Following the Principles of the Universe: Lessons from Plants on Individual and Communal Thriving.Integrative and comparative biology · 2023Article
- Population-level annotation of lncRNAs in Arabidopsis reveals extensive expression variation associated with transposable element-like silencing.The Plant cell · 2023Article
- Genetically encoded transcriptional plasticity underlies stress adaptation in Mycobacterium tuberculosis.Research square · 2023Article
- Genetically encoded transcriptional plasticity underlies stress adaptation in Mycobacterium tuberculosis.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A fundamental question in biology is how gene expression is regulated to give rise to a phenotype. However, transcriptional variability is rarely considered although it could influence the relationship between genotype and phenotype. It is known in unicellular organisms that gene expression is often noisy rather than uniform, and this has been proposed to be beneficial when environmental conditions are unpredictable. However, little is known about inter-individual transcriptional variability in multicellular organisms. Using transcriptomic approaches, we analysed gene expression variability between individual
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.