Evidence map›Paper›PMID 30697495›Full record

ArticlePeerJ2019

Transcriptome profiling reveals the role of ZBTB38 knock-down in human neuroblastoma.

Jie Chen, Chaofeng Xing, Li Yan, Yabing Wang, Haosen Wang, Zongmeng Zhang, Daolun Yu, Jie Li, Honglin Li, Jun Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Jie Chen *College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, WuHu, China.ORCID 0000-0003-1379-2628
Chaofeng Xing *College of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, WuHu, China.
Li YanDepartment of Radiation Oncology, Linyi People Hospital, Linyi, China.
Yabing WangThe First Affiliated Hospital of Wannan Medical College, WuHu, China.
Haosen WangTaizhou 4th Hospital, Taizhou, China.ORCID 0000-0002-6922-0867
Zongmeng ZhangCollege of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, WuHu, China.
Daolun YuCollege of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, WuHu, China.
Jie LiCollege of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, WuHu, China.
Honglin LiDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta State University, Augusta, GA, USA.
Jun LiCollege of Life Sciences, Anhui Provincial Key Lab of the Conservation and Exploitation of Biological Resources, Anhui Normal University, WuHu, China.
Yafei CaiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China.
Anhui Normal University · CNNanjing Agricultural University · CNAugusta University · USFirst Affiliated Hospital of Wannan Medical College · CNLinyi People's Hospital · CNTaizhou Fourth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ZBTB38 belongs to the zinc finger protein family and contains the typical BTB domains. As a transcription factor, ZBTB38 is involved in cell regulation, proliferation and apoptosis, whereas, functional deficiency of ZBTB38 induces the human neuroblastoma (NB) cell death potentially. To have some insight into the role of ZBTB38 in NB development, high throughput RNA sequencing was performed using the human NB cell line SH-SY5Y with the deletion of ZBTB38. In the present study, 2,438 differentially expressed genes (DEGs) in ZBTB38

Indexed as

Bioinformatics analysisDEGsNeuroblastomaTranscriptomeZBTB38

Identifiers

PMID30697495
PMCPMC6348090
OpenAlexW2912265581

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.