Evidence map›Paper›PMID 30700590›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

Poor Antigen Processing of Poxvirus Particles Limits CD4

Katherine S Forsyth, Brian DeHaven, Mark Mendonca, Sinu Paul, Alessandro Sette, Laurence C Eisenlohr

Abstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Surprisingly Effective Priming of CD8Journal of virology · 2020
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katherine S ForsythDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.ORCID 0000-0002-4991-1601
Brian DeHavenDepartment of Biology, La Salle University, Philadelphia, PA 19141.
Mark MendoncaDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA 19107.ORCID 0000-0002-2197-6892
Sinu PaulLa Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.
Alessandro SetteLa Jolla Institute for Allergy and Immunology, La Jolla, CA 92037.ORCID 0000-0001-7013-2250
Laurence C EisenlohrDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104; eisenlc@pennmedicine.upenn.edu.ORCID 0000-0002-8475-7910

Funding

MHCII Cross-presentation as a Driver of CD4+ T Cell Responses to PoxvirusesR01AI110542 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI EISENLOHR, LAURENCE CRANE, HERSPERGER, ADAM · 2015 to 2019
$2.6M
Myc transcriptional regulation in T-ALLF31CA206338 · NCI · UNIVERSITY OF PENNSYLVANIA · PI FORSYTH, KATHERINE · 2016 to 2018
$132k
NCI NIH HHS F31 CA206338NIAID NIH HHS HHSN272201400045CNIAID NIH HHS R01 AI110542
6 · The paper itself

Abstract

CD4

Indexed as

AnimalsAntigen PresentationCD4-Positive T-LymphocytesFemaleImmunogenicity, VaccineMiceMice, Inbred C57BLPoxviridaeVaccines, InactivatedVaccines, Inactivated

Identifiers

PMID30700590
PMCPMC6394857

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.