Evidence map›Paper›PMID 30723735›Full record

Trial reportBioMed research international2019

Effects of a New Combination of Medical Food on Endothelial Function and Lipid Profile in Dyslipidemic Subjects: A Pilot Randomized Trial.

Francesco Landi, Anna Maria Martone, Sara Salini, Beatrice Zazzara, Riccardo Calvani, Emanuele Marzetti, Antonio Nesci, Angela Di Giorgio, Bianca Giupponi, Luca Santoro and 1 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Observational
  6. Review
  7. Article
  8. The Effects of New Selective PPARJournal of diabetes research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Francesco LandiDepartment of Geriatrics, Neurosciences and Orthopedics, Fondazione Policlinico Gemelli IRCCS, Roma, Italy.ORCID 0000-0002-3472-1389
Anna Maria MartoneDepartment of Geriatrics, Neurosciences and Orthopedics, Fondazione Policlinico Gemelli IRCCS, Roma, Italy.
Sara SaliniDepartment of Geriatrics, Neurosciences and Orthopedics, Fondazione Policlinico Gemelli IRCCS, Roma, Italy.
Beatrice ZazzaraDepartment of Geriatrics, Neurosciences and Orthopedics, Fondazione Policlinico Gemelli IRCCS, Roma, Italy.
Riccardo CalvaniDepartment of Geriatrics, Neurosciences and Orthopedics, Fondazione Policlinico Gemelli IRCCS, Roma, Italy.ORCID 0000-0001-5472-2365
Emanuele MarzettiDepartment of Geriatrics, Neurosciences and Orthopedics, Fondazione Policlinico Gemelli IRCCS, Roma, Italy.ORCID 0000-0001-9567-6983
Antonio NesciDivision of Vascular Medicine, Department of Medicine-Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Angela Di GiorgioDivision of Vascular Medicine, Department of Medicine-Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Bianca GiupponiMedicina d'Urgenza e Pronto Soccorso, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Luca SantoroDivision of Vascular Medicine, Department of Medicine-Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.ORCID 0000-0003-3614-7314
Angelo SantoliquidoUniversità Cattolica del Sacro Cuore, Roma, Italy.
Agostino Gemelli University Polyclinic · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutritional approaches to improve dyslipidemias have been recently developed, but evidences on different medical foods are often incomplete. The main aim of our study was to evaluate the effects on endothelial function, lipid profile, and glucose metabolism of two different combinations of nutraceuticals, first one containing Bergavit (200 mg Citrus bergamia), Omega-3 (400 mg), Crominex 3+ (10 mcg trivalent chromium), and red yeast rice (100 mg; 5 mg monacolin K) and second one containing red yeast rice (200 mg; 3 mg monacolin K), Berberine (500 mg), Astaxanthin (0.5 mg), folic acid (200 mcg), Coenzyme Q10 (2 mg), and Policosanol (10 mg). Fifty subjects affected by dyslipidemia not requiring statin treatment were enrolled in this randomized, blind, controlled trial and submitted to blood sampling for lipid and glucose profiles and instrumental evaluation of endothelial function before and after 6 weeks of treatment with nutraceuticals. Both nutraceutical combinations improved the lipid profile; the nutraceutical containing 5 mg of monacolin K, 200 mg of the extract

Indexed as

AdultAgedBiological ProductsChromiumCitrusDietary SupplementsDyslipidemiasEndothelial CellsFatty Acids, Omega-3Fatty AlcoholsFemaleHumansLipid MetabolismLipidsMaleMiddle AgedastaxanthineBiological ProductsChromiumcoenzyme Q10Fatty Acids, Omega-3Fatty AlcoholsLipidspolicosanolred yeast riceUbiquinoneXanthophylls

Identifiers

PMID30723735
PMCPMC6339707
OpenAlexW2907344520

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.