Evidence map›Paper›PMID 30729153›Full record

ReviewNPJ microgravity2019

Express assessment of neurotoxicity of particles of planetary and interstellar dust.

Tatiana Borisova

Open access · goldAbstract readReview
In one paragraph

Review in NPJ microgravity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Space Medicines for Space Health.ACS medicinal chemistry letters · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Transient coating of γ-FeBeilstein journal of nanotechnology · 2020
    Article
  10. Fitness of Outer Membrane Vesicles FromFrontiers in microbiology · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Tatiana BorisovaDepartment of Neurochemistry, Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, 9 Leontovicha Street, Kiev, 01030 Ukraine.
Palladin Institute of Biochemistry · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Establishment of high-quality, consistent on-board assessment of the neurotoxicity of planetary, and interstellar dust particles will be required to predict their potential threat to human health during long-term space missions. This Perspective article proposes an approach for the rapid assessment of potential neurotoxicity of micro-sized and nano-sized dust particles based on experimental results with other neurotoxic particles. Capacity of particles to affect membrane potential, integrity of nerve terminals, and consequently key synaptic transmission characteristics can be assessed using a planar lipid bilayer technique by monitoring artificial membrane conductivity in the presence of particles. Preliminary neurotoxicity data of nanoparticles, including lunar and Martian dust simulants, obtained using a planar lipid bilayer technique, is compared with that acquired using more-established methodological approaches. Under space flight conditions, neurotoxicity assessments of particulate matter could be rapidly and reproducibly performed using a planar lipid bilayer technique, which does not require biological material.

Identifiers

PMID30729153
PMCPMC6361920
OpenAlexW2911655266

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.