Evidence map›Paper›PMID 30734219›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020

Temporal trends of abnormal myocardial perfusion imaging in a cohort of Italian subjects: Relation with cardiovascular risk factors.

Rosario Megna, Emilia Zampella, Roberta Assante, Carmela Nappi, Valeria Gaudieri, Teresa Mannarino, Valeria Cantoni, Roberta Green, Stefania Daniele, Ciro Gabriele Mainolfi and 3 more

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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. External validation and update of the J-ACCESS model in an Italian cohort of patients undergoing stress myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  5. Diagnostic value of clinical risk scores for predicting normal stress myocardial perfusion imaging in subjects without coronary artery calcium.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  6. Pretest models for predicting abnormal stress single-photon emission computed tomography myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  7. Nuclear cardiac imaging between implementation and globalization: The key role of integration.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  8. Article
  9. Article
  10. Temporal changes in cardiac SPECT utilization and imaging findings: Where are we going and where have we been?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Rosario MegnaInstitute of Biostructure and Bioimaging, National Council of Research, Naples, Italy.
Emilia ZampellaDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Roberta AssanteDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Carmela NappiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Valeria GaudieriInstitute of Biostructure and Bioimaging, National Council of Research, Naples, Italy.
Teresa MannarinoDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Valeria CantoniDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Roberta GreenDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Stefania DanieleInstitute of Biostructure and Bioimaging, National Council of Research, Naples, Italy.
Ciro Gabriele MainolfiDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy.
Wanda AcampaInstitute of Biostructure and Bioimaging, National Council of Research, Naples, Italy.
Mario PetrettaDepartment of Translational Medical Sciences, University Federico II, Naples, Italy.
Alberto CuocoloDepartment of Advanced Biomedical Sciences, University Federico II, Via Pansini 5, 80131, Naples, Italy. cuocolo@unina.it.
Federico II University Hospital · ITInstitute of Biostructure and Bioimaging · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe frequency of abnormal stress single-photon emission computed tomography myocardial perfusion imaging (MPS) has decreased over the past decades despite an increase in the prevalence of cardiovascular risk factors. This study evaluated the temporal trend of abnormal stress MPS and its relationship with risk factors in a cohort of Italian subjects.

methodsWe included all patients who underwent clinically indicated stress MPS at our academic center between January 2006 and December 2017. Patients were assessed for change in demographics, clinical symptoms, risk factors, and frequency of abnormal and ischemic MPS.

resultsA total of 8,886 stress MPS studies were performed (3,350 abnormal). Age, male gender, diabetes, smoking, and angina were independent predictors of abnormal MPS. There was a slight decline in the frequency of abnormal (from 39 to 36%, P < 0.05) and ischemic (from 25 to 22%, P < 0.01) MPS during the study period, while the percentage of patients with hypertension, hypercholesterolemia, smoking, and angina increased. The Cochran-Mantel-Haenszel test indicates that the likelihood of having an abnormal MPS did not change over time for age, diabetes, smoking, and a history of coronary artery disease (CAD), increased for hypertension and hypercholesterolemia and decreased for male compared to female gender.

conclusionsIn our cohort of Italian subjects, there was a slight temporal decline in the frequency of abnormal and ischemic MPS despite an increase over time in the prevalence of many cardiac risk factors. These results strengthen the need to develop more effective strategies for appropriately referring patients to cardiac imaging procedures.

Indexed as

AgedBlood PressureCardiovascular DiseasesCoronary Artery DiseaseFemaleHeartHumansItalyMaleMiddle AgedMyocardial IschemiaMyocardial Perfusion ImagingProspective StudiesRisk FactorsSoftwareTechnetium Tc 99m SestamibiTechnetium Tc 99m SestamibiCADdiagnostic and prognostic applicationMPISPECT

Identifiers

PMID30734219
OpenAlexW2913161996

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.