Evidence map›Paper›PMID 30737314›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Disruption of RAB-5 Increases EFF-1 Fusogen Availability at the Cell Surface and Promotes the Regenerative Axonal Fusion Capacity of the Neuron.

Casey Linton, M Asrafuzzaman Riyadh, Xue Yan Ho, Brent Neumann, Rosina Giordano-Santini, Massimo A Hilliard

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Journal of biosciences · 2025
    Review
  2. Extracellular vesicles.Genetics · 2024
    Review
  3. Article
  4. Article
  5. Fusogen-mediated neuron-neuron fusion disrupts neural circuit connectivity and alters animal behavior.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Casey LintonClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia, and.
M Asrafuzzaman RiyadhClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia, and.ORCID 0000-0001-8155-9129
Xue Yan HoClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia, and.ORCID 0000-0002-6700-1708
Brent NeumannNeuroscience Program, Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria 3800, Australia.ORCID 0000-0002-7317-9385
Rosina Giordano-SantiniClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia, and m.hilliard@uq.edu.au r.giordanosantini@uq.edu.au.ORCID 0000-0001-5899-9409
Massimo A HilliardClem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia, and m.hilliard@uq.edu.au r.giordanosantini@uq.edu.au.ORCID 0000-0001-7458-5812
The University of Queensland · AUMonash University · AU

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Following a transection injury to the axon, neurons from a number of species have the ability to undergo spontaneous repair via fusion of the two separated axonal fragments. In the nematode

Indexed as

AnimalsAxonsCaenorhabditis elegans ProteinsCell FusionCell MembraneEndocytosisExtracellular SpaceMembrane GlycoproteinsMembrane ProteinsMutationNerve RegenerationNeuronsVesicular Transport ProteinsCaenorhabditis elegans ProteinsEFF-1 protein, C elegansMembrane GlycoproteinsMembrane ProteinsRab-5 protein, C elegansVesicular Transport Proteinsaxonal fusionaxonal regenerationC. elegansendocytosisfusogenRAB-5

Identifiers

PMID30737314
PMCPMC6462446
OpenAlexW2912708288

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.