Evidence map›Paper›PMID 30737658›Full record

ArticleGeneral thoracic and cardiovascular surgery2019

Current mechanisms of low graft flow and conduit choice for the right coronary artery based on the severity of native coronary stenosis and myocardial flow demand.

Hiroyuki Nakajima, Akitoshi Takazawa, Akihiro Yoshitake, Chiho Tokunaga, Masato Tochii, Jun Hayashi, Hiroaki Izumida, Daisuke Kaneyuki, Toshihisa Asakura, Atsushi Iguchi

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Article in General thoracic and cardiovascular surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroyuki NakajimaDepartment of Cardiovascular Surgery, International Medical Centre, Saitama Medical University, 1397-1, Yamane Hidaka, Saitama, 350-1298, Japan. hn00504@ybb.ne.jp.ORCID http://orcid.org/0000-0003-1194-7091
Akitoshi TakazawaDepartment of Cardiovascular Surgery, International Medical Centre, Saitama Medical University, 1397-1, Yamane Hidaka, Saitama, 350-1298, Japan.
Akihiro YoshitakeDepartment of Cardiovascular Surgery, International Medical Centre, Saitama Medical University, 1397-1, Yamane Hidaka, Saitama, 350-1298, Japan.
Chiho TokunagaDepartment of Cardiovascular Surgery, International Medical Centre, Saitama Medical University, 1397-1, Yamane Hidaka, Saitama, 350-1298, Japan.
Masato TochiiDepartment of Cardiovascular Surgery, International Medical Centre, Saitama Medical University, 1397-1, Yamane Hidaka, Saitama, 350-1298, Japan.
Jun HayashiDepartment of Cardiovascular Surgery, International Medical Centre, Saitama Medical University, 1397-1, Yamane Hidaka, Saitama, 350-1298, Japan.
Hiroaki IzumidaDepartment of Cardiovascular Surgery, International Medical Centre, Saitama Medical University, 1397-1, Yamane Hidaka, Saitama, 350-1298, Japan.
Daisuke KaneyukiDepartment of Cardiovascular Surgery, International Medical Centre, Saitama Medical University, 1397-1, Yamane Hidaka, Saitama, 350-1298, Japan.
Toshihisa AsakuraDepartment of Cardiovascular Surgery, International Medical Centre, Saitama Medical University, 1397-1, Yamane Hidaka, Saitama, 350-1298, Japan.
Atsushi IguchiDepartment of Cardiovascular Surgery, International Medical Centre, Saitama Medical University, 1397-1, Yamane Hidaka, Saitama, 350-1298, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe investigated current mechanisms causing low graft flow (LGF) following coronary artery bypass grafting, particularly for the right coronary artery (RCA).

methodsWe retrospectively assessed 230 individual bypass grafts as the sole bypass graft for the RCA using preoperative and postoperative quantitative angiography. Overall, 155 in-situ gastroepiploic arteries (GEAs) and 75 saphenous vein grafts (SVGs) were included. The size and status of the revascularised area were examined to determine whether these factors were associated with LGF (defined as ≤ 20 mL/min with intraoperative flowmetry). A distal lesion was defined as stenosis at segment #4, whereas a proximal lesion was stenosis at #1, #2 and #3.

resultsGraft flow in the SVG and the GEA for distal lesion was significantly less compared with that for proximal lesion (34 ± 26 vs. 60 ± 46, p < 0.0001 and 22 ± 12 vs. 43 ± 28, p = 0.0004, respectively). For proximal lesion, LGF was significantly more frequent when the minimal luminal diameter was over 1.27 compared with when it was less than 1.27 (p = 0.02). Prior myocardial infarction significantly correlated with LGF in the GEA (p = 0.007) and the SVG (p = 0.03). In 55 bypass grafts with LGF, the causes were competitive flow in 20.0%, small revascularised area in 38.1% and prior myocardial infarction in 32.7%.

conclusionsAlong with the current strategy based on the severity of native coronary stenosis, the incidence of competitive flow decreased remarkably. This resulted in flow demand, myocardial status and collateral vessels more influential on graft patency.

Indexed as

Coronary Artery BypassAgedBlood Flow VelocityBlood Vessel ProsthesisCoronary AngiographyCoronary StenosisCoronary VesselsFemaleGastroepiploic ArteryHumansMaleMiddle AgedMyocardial InfarctionMyocardiumPostoperative PeriodRegional Blood FlowArterial graftCoronary artery bypass graftFlow demandOff-pumpTransit time flowmetry

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.