Evidence map›Paper›PMID 30740089›Full record

ReviewFrontiers in endocrinology2018

The Mechanism and Pathways of Dopamine and Dopamine Agonists in Prolactinomas.

Xiaoshuang Liu, Chao Tang, Guodao Wen, Chunyu Zhong, Jin Yang, Junhao Zhu, Chiyuan Ma

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
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  5. Review
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  9. Article
  10. Review
  11. The dopaminergic control of Cushing's syndrome.Journal of endocrinological investigation · 2022
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Endocrinopathies and Male Infertility.Life (Basel, Switzerland) · 2021
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xiaoshuang LiuThe State Key Laboratory of Pharmaceutical Biotechnology and Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, School of Life Science, NJU Advanced Institute for Life Sciences, Nanjing University, Nanjing, China.
Chao TangDepartment of Neurosurgery, School of Medicine, Jinling Hospital, Nanjing University, Nanjing, China.
Guodao WenTungwah Hospital of Sun Yat-Sen University, Dongguan, China.
Chunyu ZhongSchool of Medicine, Nanjing Medical University, Nanjing, China.
Jin YangSchool of Medicine, Nanjing Medical University, Nanjing, China.
Junhao ZhuSchool of Medicine, Nanjing Medical University, Nanjing, China.
Chiyuan MaDepartment of Neurosurgery, School of Medicine, Jinling Hospital, Nanjing University, Nanjing, China.
Nanjing Medical University · CNNanjing University · CNTung Wah Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine agonists such as bromocriptine and cabergoline are the predominant treatment drugs for prolactinoma by inhibiting prolactin secretion and shrinking tumor size. However, the pathways of either dopamine or its agonists that lead to the death of cells are incompletely understood and some are even conflicting conclusions. The main aim of this paper is to review the different pathways of dopamine and its agonists in prolactinomas to help to gain a better understanding of their functions and drug resistance mechanisms.

Indexed as

bromocriptinecabergolinedopamine agonistsprogrammed cell deathprolactinomas

Identifiers

PMID30740089
PMCPMC6357924
OpenAlexW2912933248

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.