Evidence map›Paper›PMID 30756334›Full record

ArticleMolecular biology reports2019

Isoflavones prevent oxidative stress and inhibit the activity of the enzyme monoamine oxidase in vitro.

Izaviany da Silva Schmitz, Larissa Finger Schaffer, Alcindo Busanello, Catiuscia Molz de Freitas, Roselei Fachinetto, Luis Ricardo Peroza

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Izaviany da Silva SchmitzCurso de Biomedicina, Universidade Franciscana (UFN), Santa Maria, Rio Grande do Sul, Brazil.
Larissa Finger SchafferCurso de Biomedicina, Universidade Franciscana (UFN), Santa Maria, Rio Grande do Sul, Brazil.
Alcindo BusanelloPrograma de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.
Catiuscia Molz de FreitasPrograma de Pós-Graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.
Roselei FachinettoPrograma de Pós-Graduação em Farmacologia, Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.
Luis Ricardo PerozaMestrado em Ciências da Saúde e da Vida, Universidade Franciscana (UFN), Santa Maria, Rio Grande do Sul, 97010-032, Brazil. perozalr@gmail.com.ORCID http://orcid.org/0000-0002-5361-0043
Universidade Federal de Santa Maria · BRUniversidade Franciscana · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 475210/2013-1Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul 2080-2551/13-5-PqG-001/2013
6 · The paper itself

Abstract

Oxidative stress occurs due to an imbalance between antioxidant defenses and pro-oxidant agents in brain. This condition has been associated to the pathogenesis of several brain diseases; therefore, increasing the use of compounds that exert antioxidant activity. Thus, the objective of this study was to evaluate, in vitro, the effect of isoflavones in: (1) lipid peroxidation, catalase activity and thiol groups in the presence of pro-oxidants: sodium nitroprusside or Fe

Indexed as

AnimalsBrainCatalaseIsoflavonesLipid PeroxidationMaleMonoamine OxidaseMonoamine Oxidase InhibitorsNitroprussideOxidation-ReductionOxidative StressRatsRats, WistarReactive Oxygen SpeciesCatalaseIsoflavonesMonoamine OxidaseMonoamine Oxidase InhibitorsNitroprussideReactive Oxygen SpeciesAntioxidantIsoflavonesMonoamine oxidaseOxidative stress

Identifiers

PMID30756334
OpenAlexW2913189568

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.