ArticlePloS one2019
Association between physical activity and change in renal function in patients after acute myocardial infarction.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Rehabilitation for Cardiorenal Multimorbidity: Epidemiology, Functional Phenotypes, and Effects on Physical Function, Renal Trajectory, and Prognosis.Journal of clinical medicine · 2026Review
- Physical Inactivity Syndrome: A Risk Factor and Target for Intervention-A Narrative Review.Progress in rehabilitation medicine · 2025Review
- Article
- Multimorbidity and Multiple Disabilities: Present Status and the Roles of Rehabilitation.Journal of clinical medicine · 2024Review
- Can Functional Motor Capacity Influence Mortality in Advanced Chronic Kidney Disease Patients?Nutrients · 2024Observational
- Impact of moderate to vigorous intensity physical activity on change in renal function in patients after acute myocardial infarction.Heart and vessels · 2024Observational
- Renal Rehabilitation: Present and Future Perspectives.Journal of clinical medicine · 2024Review
- Onset of the COVID-19 pandemic reduced active time in patients with implanted cardiac devices.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2022Article
- Physical Activity and Exercise for Cardiorespiratory Health and Fitness in Chronic Kidney Disease.Reviews in cardiovascular medicine · 2022Article
- The Association between Health-Enhancing Physical Activity and Quality of Life in Patients with Chronic Kidney Disease: Propensity Score Matching Analysis.International journal of environmental research and public health · 2022Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCombined renal dysfunction worsens the subsequent prognosis in patients after acute myocardial infarction (AMI). Therefore, establishing a therapeutic modality to maintain or improve renal function in AMI patients is necessary. This study aimed to elucidate the association between physical activity level and change in renal function in such patients.
designProspective and observational study.
methodsWe enrolled 41 patients (35 men; average age, 67.5 ± 12.6 years) after AMI onset. Blood biochemistry, urinalysis, and physical function tests were conducted at discharge and 3 months after discharge. Renal function was evaluated based on cystatin C based-estimated glomerular filtration rate (eGFRcys). The number of steps was recorded for 3 months post-discharge. Generalized estimating equations (GEE) was used to test the association between physical activity level and within-patient changes in eGFRcys.
resultsPatients were stratified into low (n = 21; number of steps, 2335 ± 1219 steps/day) and high groups (n = 20; number of steps, 7102 ± 2365 steps/day). eGFRcys significantly increased from baseline to after 3 months in the high group (76.5 ± 13.8 to 83.2 ± 16.0 mL/min/1.73 m2, q = 0.004), whereas no significant change was observed in the low group (65.1 ± 15.9 to 62.2 ± 20.2 mL/min/1.73 m2, q = 0.125). Result of GEE adjusted for potential confounding variables showed a significant positive association between physical activity level and within-patient changes in eGFRcys (p = 0.003). Changes in eGFRcys was -2.9 mL/min/1.73 m2 among low group versus +6.7 mL/min/1.73 m2 among high group.
conclusionsPhysical activity level was positively associated with changes in renal function, demonstrating that high physical activity may suppress renal function decline in patients after AMI.
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