ArticleThe British journal of radiology2019
Inter-rater and scan-rescan reproducibility of the detection of intracranial atherosclerosis on contrast-enhanced 3D vessel wall MRI.
Article in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Imaging endpoints of intracranial atherosclerosis using vessel wall MR imaging: a systematic review.Neuroradiology · 2021Pooled it
- MR Intracranial Vessel Wall Imaging: A Systematic Review.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020Pooled it
- Expert consensus on intracranial vessel wall MRI in cerebrovascular disease: Society for Magnetic Resonance Angiography recommendations.European radiology · 2026Review
- Voxel-Wise Quantification and Multi-planar Visualization of Plaque Contrast Enhancement in Intracranial Vessel Wall MRI.medRxiv : the preprint server for health sciences · 2025Article
- Inter-rater reliability of atherosclerotic plaque enhancement on 7 T vessel wall MRI: Comparison with quantitative analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Plaque Evolution and Vessel Wall Remodeling of Intracranial Arteries: A Prospective, Longitudinal Vessel Wall MRI Study.Journal of magnetic resonance imaging : JMRI · 2024Article
- Vessel Wall Imaging in Cryptogenic Stroke.Radiologic clinics of North America · 2023Review
- Advanced cross-sectional imaging of cerebral aneurysms.The British journal of radiology · 2023Review
- Idiopathic intracranial hypertension imaging approaches and the implications in patient management.The British journal of radiology · 2022Review
- Survey of the American Society of Neuroradiology Membership on the Use and Value of Intracranial Vessel Wall MRI.AJNR. American journal of neuroradiology · 2022Article
- Vessel Wall MR Imaging in the Pediatric Head and Neck.Magnetic resonance imaging clinics of North America · 2021Review
- Comparison of time-of-flight MR angiography and intracranial vessel wall MRI for luminal measurements relative to CT angiography.The British journal of radiology · 2021Article
- Vascularity and Dynamic Contrast-Enhanced Breast Magnetic Resonance Imaging.Frontiers in radiology · 2021Review
- Imaging of intracranial atherosclerotic plaques using 3.0 T and 7.0 T magnetic resonance imaging-current trends and future perspectives.Cardiovascular diagnosis and therapy · 2020Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe objective is to establish interscan, inter- and intra-rater reproducibility of a multicontrast three-dimensional contrast-enhanced intracranial vessel wall (IVW) MRI protocol with 0.6 mm acquired (0.3 mm interpolated) isotropic resolution in the detection of intracranial atherosclerosis.
methodsSubjects with established intracranial atherosclerosis were prospectively recruited and underwent two contrast-enhanced three-dimensional IVW scans within a 2-week period. Four raters with varying degrees of vessel wall imaging interpretation experience, through an iterative training process developed guidelines for plaque identification with no, possible and definite plaque categories. Using these guidelines, the raters reviewed the cases in pairs (consensus rating), while blinded to the interpretations of the other pair, clinical reports and patient history. The rater pairs reviewed 19 segments per patient for the presence and location of atherosclerotic plaques. Inter-scan, inter rater and intra rater reproducibility were assessed.
results19 subjects were scanned twice, with 361 total segments reviewed and 304-324 evaluable segments analyzed in the different reproducibility assessments. Overall inter-rater agreement for possible and definite plaque was 88.9 % [κ = 0.73; 95% confidence interval (CI) (0.62-0.81)], inter-scan/intra-rater agreement was 82.1 % [κ = 0.58; 95% CI (0.48-0.70)] and inter-scan/inter-rater agreement of 84.5% [κ = 0.64; 95% CI (0.51 - 0.76)].
conclusionContrast-enhanced IVW imaging, with the utilization of detailed plaque definition guidelines for image review, can be a reproducible technique for the evaluation of intracranial atherosclerosis. ADVANCES IN KNOWLEDGE: This work is the first to establish reproducibility of IVW for plaque identification with and without contrast. Reproducibility using contrast is important as most IVW applications rely on lesion enhancement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.