Evidence map›Paper›PMID 30790552›Full record

ReviewChest2019

OSA and Cardiovascular Risk in Pediatrics.

David F Smith, Raouf S Amin

Open access · greenAbstract readReview
In one paragraph

Review in Chest, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 104 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. [Differential study on sleep architecture and sleep subtypes in children with OSA in different weight states].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Article
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Review
  11. Article
  12. Research advances in children's sleep and vitamin D levels.Annals of pediatric endocrinology & metabolism · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

David F SmithDivision of Pediatric Otolaryngology-Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Division of Pulmonary and Sleep Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH.
Raouf S AminDivision of Pulmonary and Sleep Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. Electronic address: raouf.amin@cchmc.org.
Cincinnati Children's Hospital Medical Center · USUniversity of Cincinnati Medical Center · US

Funding

Vascular Functions in Children with Sleep Disordered BreathingR01HL080670 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI AMIN, RAOUF S. · 2006 to 2010
$2.8M
Mechanisms Mediating C/V Disease in Children with OSAR01HL070907 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI AMIN, RAOUF S · 2003 to 2007
$1.8M
Circadian Clock Dysregulation in a Model of Obstructive Sleep ApneaK08HL148551 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI SMITH, DAVID F · 2019 to 2023
$818k
NHLBI NIH HHS K08 HL148551NHLBI NIH HHS R01 HL070907NHLBI NIH HHS R01 HL080670
6 · The paper itself

Abstract

OSA occurs in approximately 1% to 5% of children in the United States. Long-term cardiovascular risks associated with OSA in the adult population are well documented. Although changes in BP regulation occur in children with OSA, the pathways leading to chronic cardiovascular risks of OSA in children are less clear. Risk factors associated with cardiovascular disease in adult populations could carry the same future risk for children. It is imperative to determine whether known mechanisms of cardiovascular diseases in adults are like those that lead to pediatric disease. Early pathophysiologic changes may lead to a lifetime burden of cardiovascular disease and early mortality. With this perspective in mind, our review discusses pathways leading to cardiovascular pathology in children with OSA and provides a comprehensive overview of recent research findings related to cardiovascular sequelae in the pediatric population.

Indexed as

Blood PressureCardiovascular DiseasesChildHumansSleep Apnea, ObstructivecardiovascularOSApediatricsrisk factors

Identifiers

PMID30790552
PMCPMC7926994
OpenAlexW2915751260

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.