ReviewTrends in endocrinology and metabolism: TEM2019
Mathematical Modelling of Endocrine Systems.
Review in Trends in endocrinology and metabolism: TEM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Constant light disrupts biological rhythms and worsens sleep quality but does not elevate blood pressure in female rats.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Unifying regulatory motifs in endocrine circuits.Nature communications · 2025Article
- Article
- Computational simulations of endocrine bone diseases related to pathological glandular PTH secretion using a multi-scale bone cell population model.Frontiers in bioengineering and biotechnology · 2025Article
- Short-term blood pressure variability and reduced cytosolic calcium levels.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- HormoneBayes: A novel Bayesian framework for the analysis of pulsatile hormone dynamics.PLoS computational biology · 2024Article
- Physiologic hormone administration improves HbA1C in Native Americans with type 2 diabetes: A retrospective study and review of insulin secretion and action.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Review
- Predicting Sex in White Rhinoceroses: A Statistical Model for Conservation Management.Animals : an open access journal from MDPI · 2023Article
- Functional characteristics of hub and wave-initiator cells in β cell networks.Biophysical journal · 2023Article
- Modeling the progression of Type 2 diabetes with underlying obesity.PLoS computational biology · 2023Article
- Systems bioengineering approaches for developmental toxicology.Computational and structural biotechnology journal · 2023Review
- Chemogenetic activation of PVN CRH neurons disrupts the estrous cycle and LH dynamics in female mice.Frontiers in endocrinology · 2023Article
- Neural substrates underlying rhythmic coupling of female reproductive and thermoregulatory circuits.Frontiers in physiology · 2023Review
- The effect of forskolin and the role of Epac2A during activation, activity, and deactivation of beta cell networks.Frontiers in endocrinology · 2023Article
- A comparative recognition research on excretory organism in medical applications using artificial neural networks.Frontiers in bioengineering and biotechnology · 2023Article
- Quantitative approaches in clinical reproductive endocrinology.Current opinion in endocrine and metabolic research · 2022Review
- Circadian clocks and their integration with metabolic and reproductive systems: our current understanding and its application to the management of dairy cows.Journal of animal science · 2022Review
- Analysis of wearable time series data in endocrine and metabolic research.Current opinion in endocrine and metabolic research · 2022Review
- Multi-Timescale Rhythmicity of Blood Glucose and Insulin Delivery Reveals Key Advantages of Hybrid Closed Loop Therapy.Journal of diabetes science and technology · 2022Article
- The transition between acute and chronic infections in light of energy control: a mathematical model of energy flow in response to infection.Journal of the Royal Society, Interface · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Hormone rhythms are ubiquitous and essential to sustain normal physiological functions. Combined mathematical modelling and experimental approaches have shown that these rhythms result from regulatory processes occurring at multiple levels of organisation and require continuous dynamic equilibration, particularly in response to stimuli. We review how such an interdisciplinary approach has been successfully applied to unravel complex regulatory mechanisms in the metabolic, stress, and reproductive axes. We discuss how this strategy is likely to be instrumental for making progress in emerging areas such as chronobiology and network physiology. Ultimately, we envisage that the insight provided by mathematical models could lead to novel experimental tools able to continuously adapt parameters to gradual physiological changes and the design of clinical interventions to restore normal endocrine function.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.