Evidence map›Paper›PMID 30809046›Full record

ArticleScientific reports2019

Genome-wide association study suggests impact of chromosome 10 rs139401390 on kidney function in patients with coronary artery disease.

Boris Schmitz, Marcus E Kleber, Malte Lenders, Graciela E Delgado, Christiane Engelbertz, Jie Huang, Hermann Pavenstädt, Günter Breithardt, Stefan-Martin Brand, Winfried März and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Boris SchmitzInstitute of Sports Medicine, Molecular Genetics of Cardiovascular Disease, University Hospital Muenster, Muenster, Germany.
Marcus E KleberMedical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.ORCID 0000-0003-0663-7275
Malte LendersInternal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.
Graciela E DelgadoMedical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.
Christiane EngelbertzInternal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.
Jie HuangDepartment of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
Hermann PavenstädtInternal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.
Günter BreithardtDivision of Vascular Medicine, Department of Cardiovascular Medicine, University Hospital Muenster, Muenster, Germany.
Stefan-Martin BrandInstitute of Sports Medicine, Molecular Genetics of Cardiovascular Disease, University Hospital Muenster, Muenster, Germany.
Winfried MärzMedical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.
Eva BrandInternal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany. Eva.Brand@ukmuenster.de.
University Hospital Münster · DEHeidelberg University · DEMedical University of Graz · ATWellcome Sanger Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease (CKD) is an independent risk factor for onset and progression of coronary artery disease (CAD). Discovery of predisposing loci for kidney function in CAD patients was performed using a genome-wide association approach. Inclusion criteria were CAD with ≥50% stenosis (≥1 coronary artery) and a creatinine-based estimated glomerular filtration rate (eGFR) of 30-75 ml/min/1.73 m

Indexed as

Genome-Wide Association StudyAgedChromosomes, Human, Pair 10Coronary Artery DiseaseCross-Sectional StudiesDisease ProgressionFemaleGlomerular Filtration RateHumansMalePrognosisRenal Insufficiency, ChronicRisk Factors

Identifiers

PMID30809046
PMCPMC6391429
OpenAlexW2916422457

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.