Evidence map›Paper›PMID 30809242›Full record

ArticleFrontiers in genetics2019

k-Skip-n-Gram-RF: A Random Forest Based Method for Alzheimer's Disease Protein Identification.

Lei Xu, Guangmin Liang, Changrui Liao, Gin-Den Chen, Chi-Chang Chang

Abstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

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  13. Genomic Variation Prediction: A Summary From Different Views.Frontiers in cell and developmental biology · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Identifying Protein Biomarkers in Blood for Alzheimer's Disease.Frontiers in cell and developmental biology · 2020
    Article
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lei XuSchool of Electronic and Communication Engineering, Shenzhen Polytechnic, Shenzhen, China.
Guangmin LiangSchool of Electronic and Communication Engineering, Shenzhen Polytechnic, Shenzhen, China.
Changrui LiaoKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, China.
Gin-Den ChenDepartment of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, Taiwan.
Chi-Chang ChangSchool of Medical Informatics, Chung Shan Medical University, Taichung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, a computational method based on machine learning technique for identifying Alzheimer's disease genes is proposed. Compared with most existing machine learning based methods, existing methods predict Alzheimer's disease genes by using structural magnetic resonance imaging (MRI) technique. Most methods have attained acceptable results, but the cost is expensive and time consuming. Thus, we proposed a computational method for identifying Alzheimer disease genes by use of the sequence information of proteins, and classify the feature vectors by random forest. In the proposed method, the gene protein information is extracted by adaptive k-skip-n-gram features. The proposed method can attain the accuracy to 85.5% on the selected UniProt dataset, which has been demonstrated by the experimental results.

Indexed as

Alzheimer's diseasegene codingn-gram modelrandom forestsequence information

Identifiers

PMID30809242
PMCPMC6379451

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.