Evidence map›Paper›PMID 30810061›Full record

Trial reportAmerican journal of physiology. Renal physiology2019

Effects of aerobic exercise on vascular function in nondialysis chronic kidney disease: a randomized controlled trial.

Danielle L Kirkman, Meghan G Ramick, Bryce J Muth, Joseph M Stock, Ryan T Pohlig, Raymond R Townsend, David G Edwards

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of physiology. Renal physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 14 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 14 syntheses or guidelines pooled it, 65 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Danielle L KirkmanDepartment of Kinesiology and Health Sciences, Virginia Commonwealth University , Richmond, Virginia.
Meghan G RamickDepartment of Kinesiology, West Chester University , West Chester, Pennsylvania.
Bryce J MuthDepartment of Kinesiology and Applied Physiology, University of Delaware , Newark, Delaware.
Joseph M StockDepartment of Kinesiology and Applied Physiology, University of Delaware , Newark, Delaware.
Ryan T PohligCollege of Health Sciences, University of Delaware , Newark, Delaware.
Raymond R TownsendPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennyslvania.
David G EdwardsDepartment of Kinesiology and Applied Physiology, University of Delaware , Newark, Delaware.ORCID 0000-0002-5098-6678
University of Delaware · USUniversity of Pennsylvania · USVirginia Commonwealth University · USWest Chester University · US

Funding

Exercise and Vascular Function in Chronic Kidney DiseaseR01HL113514 · NHLBI · UNIVERSITY OF DELAWARE · PI EDWARDS, DAVID G · 2013 to 2015
$1.2M
NHLBI NIH HHS R01 HL113514
6 · The paper itself

Abstract

Endothelial dysfunction and arterial stiffness are nontraditional risk factors of chronic kidney disease (CKD)-related cardiovascular disease (CVD) that could be targeted with exercise. This study investigated the effect of moderate to vigorous aerobic exercise on vascular function in nondialysis CKD. In this randomized, controlled trial, 36 nondialysis patients with CKD (means ± SE, age: 58 ± 2 yr, estimated glomerular filtration rate: 44 ± 2 ml·min

Indexed as

Exercise TherapyMicrocirculationVascular StiffnessVasodilationAdultAgedBrachial ArteryFemaleHumansMaleMicrovesselsMiddle AgedRecovery of FunctionRenal Insufficiency, ChronicSkinTime Factorscardiovascular diseaseendotheliumexercise therapyrenal insufficiency, chronicvascular

Identifiers

PMID30810061
PMCPMC6580257
OpenAlexW2917619906

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.