ReviewObesity reviews : an official journal of the International Association for the Study of Obesity2019
A comprehensive diagnostic approach to detect underlying causes of obesity in adults.
Review in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05837468 (Better App), which is not on this map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Better App: (Further-)Development and Evaluation of a Digital Lifestyle Programme Based on Subtypes for Overweight or Obese People
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Weight Maintenance after Dietary Weight Loss: Systematic Review and Meta-Analysis on the Effectiveness of Behavioural Intensive Intervention.Nutrients · 2022Pooled it
- Cross-sectional relation of long-term glucocorticoids in hair with anthropometric measurements and their possible determinants: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Pooled it
- Setmelanotide in Bardet-Biedl Syndrome: A 52-Week Comparison of Phase 3 Trial Participants With a Matched Registry Cohort.Obesity (Silver Spring, Md.) · 2026Trial
- Impact of Obesity on Individuals in Saudi Arabia: A Real-World Patient and Physician Survey.Advances in therapy · 2026Article
- Functional characterisation of obesity-associated MRAP2 variants on MC4R and GHSR signalling.Human molecular genetics · 2026Article
- Demographics and obesity using a machine learning approach: Iranian National Obesity Registry (IRNOR).Journal of education and health promotion · 2026Article
- Delphi Consensus Among French Obesity Experts on Clinical Recommendations for Drug Prescription in Patients With Severe Obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Review
- Obesity care in Chinese adults: from evidence to clinical practice.Precision clinical medicine · 2025Review
- Corticosteroid Use and Long-Term Changes in Weight and Waist Circumference: The Lifelines Cohort Study.The Journal of clinical endocrinology and metabolism · 2025Article
- Nutritional and Energy Profile of "No Added Sugar" Products Versus Their Conventional Counterparts on the Polish Food Market.Nutrients · 2025Article
- Comparison of time-restricted eating and a six-meal diet: Effects on body composition and biochemical parameters.Asia Pacific journal of clinical nutrition · 2025Article
- Obesity and its management in primary care setting.Journal of diabetes and its complications · 2025Review
- Novel Insights into Somatic Comorbidities in Children and Adolescents Across Psychiatric Diagnoses: An Explorative Study.Child psychiatry and human development · 2025Article
- Antiobesity Pharmacotherapy for Patients With Genetic Obesity Due to Defects in the Leptin-Melanocortin Pathway.Endocrine reviews · 2025Review
- Glucocorticoids and HPA axis regulation in the stress-obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions.Clinical obesity · 2025Review
- Weight Reduction with GLP-1 Agonists and Paths for Discontinuation While Maintaining Weight Loss.Biomolecules · 2025Review
- Patient Perspectives on Impact of Weight and Weight Stigma on Breast and Cervical Cancer Treatment: A Qualitative Study.Cancer medicine · 2025Article
- Management of obesities with a cause specific approach.International journal of obesity (2005) · 2025Review
- Understanding the dynamics driving obesity in socioeconomically deprived urban neighbourhoods: an expert-based systems map.BMC medicine · 2025Article
- Oral semaglutide for the treatment of obesity: a retrospective real-world study.Frontiers in endocrinology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity is a worldwide growing problem. When confronted with obesity, many health care providers focus on direct treatment of the consequences of adiposity. We plead for adequate diagnostics first, followed by an individualized treatment. We provide experience-based and evidence-based practical recommendations (illustrated by clinical examples), to detect potential underlying diseases and contributing factors. Adult patients consulting a doctor for weight gain or obesity should first be clinically assessed for underlying diseases, such as monogenetic or syndromic obesity, hypothyroidism, (cyclic) Cushing syndrome, polycystic ovarian syndrome (PCOS), hypogonadism, growth hormone deficiency, and hypothalamic obesity. The most important alarm symptoms for genetic obesity are early onset obesity, dysmorphic features/congenital malformations with or without intellectual deficit, behavioral problems, hyperphagia, and/or striking family history. Importantly, also common contributing factors to weight gain should be investigated, including medication (mainly psychiatric drugs, (local) corticosteroids, insulin, and specific β-adrenergic receptor blockers), sleeping habits and quality, crash diets and yoyo-effect, smoking cessation, and alcoholism. Other associated conditions include mental factors such as chronic stress or binge-eating disorder and depression.Identifying and optimizing the underlying diseases, contributing factors, and other associated conditions may not only result in more effective and personalized treatment but could also reduce the social stigma for patients with obesity.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.