Evidence map›Paper›PMID 30823679›Full record

ArticleMolecules (Basel, Switzerland)2019

Study on Antidepressant Activity of Pseudo-Ginsenoside HQ on Depression-Like Behavior in Mice.

Li-Xue Chen, Zeng Qi, Zi-Jun Shao, Shan-Shan Li, Yu-Li Qi, Kun Gao, Song-Xin Liu, Zhuo Li, Yin-Shi Sun, Ping-Ya Li

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. 7,8-DHF Modulates Aggressive Behavior inAnimals : an open access journal from MDPI · 2025
    Article
  6. Article
  7. Complementary and alternative medicine on cognitive defects and neuroinflammation after sepsis.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024
    Article
  8. Neurotrophic Natural Products.Progress in the chemistry of organic natural products · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. PPARγ and Cognitive Performance.International journal of molecular sciences · 2019
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Li-Xue ChenInstitute of Special Animals and Plants Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. 82101172456@caas.cn.
Zeng QiSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China. qizeng95@163.com.ORCID 0000-0002-3553-0349
Zi-Jun ShaoInstitute of Special Animals and Plants Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. shaozijun2017@163.com.
Shan-Shan LiInstitute of Special Animals and Plants Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. Lishanshan@caas.cn.
Yu-Li QiInstitute of Special Animals and Plants Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. 15568871905@163.com.
Kun GaoInstitute of Special Animals and Plants Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. GaoK2018@163.com.
Song-Xin LiuInstitute of Special Animals and Plants Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. liusx2018@163.com.
Zhuo LiSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China. zhuoli198602@gmail.com.
Yin-Shi SunInstitute of Special Animals and Plants Sciences, Chinese Academy of Agricultural Sciences, Changchun 130112, China. sunyinshi2015@163.com.ORCID 0000-0002-1889-4984
Ping-Ya LiSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China. lipy@jlu.edu.cn.
Chinese Academy of Agricultural Sciences · CNJilin University · CN

Funding

the Scientific and Technologic Foundation of Jilin Province 20160520048JH, 201603078YY and 20180311037YY
6 · The paper itself

Abstract

Suppressive effects of ginsenoside Rh₂ (Rh₂), (24

Indexed as

AnimalsAntidepressive AgentsBehavior, AnimalBrain-Derived Neurotrophic FactorDepressionDisease Models, AnimalGene Expression RegulationGinsenosidesHindlimb SuspensionHumansInterleukin-6LipopolysaccharidesMiceNF-kappa BSignal TransductionSwimming3-O-glucopyranosyl-3,12,25-trihydroxydammar-20(22)-eneAntidepressive AgentsBdnf protein, mouseBrain-Derived Neurotrophic Factorginsenoside Rh2GinsenosidesInterleukin-6LipopolysaccharidesNF-kappa BTriterpenesTumor Necrosis Factor-alpha(24R)-pseudo-ginsenoside HQ(24S)-pseudo-ginsenoside HQginsenoside Rh2LPS-induced depression

Identifiers

PMID30823679
PMCPMC6429332
OpenAlexW2916274749

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.